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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1980 2
1981 5
1982 2
1983 7
1984 2
1985 4
1986 4
1987 4
1988 7
1989 6
1990 12
1991 10
1992 4
1993 5
1994 4
1995 3
1997 14
1998 7
1999 6
2000 6
2001 9
2002 10
2003 7
2004 8
2005 11
2006 10
2007 12
2008 14
2009 12
2010 10
2011 13
2012 24
2013 19
2014 15
2015 10
2016 12
2017 15
2018 17
2019 12
2020 9
2021 12
2022 7
2023 5
2024 4

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369 results

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Page 1
Mepolizumab treatment in patients with severe eosinophilic asthma.
Ortega HG, Liu MC, Pavord ID, Brusselle GG, FitzGerald JM, Chetta A, Humbert M, Katz LE, Keene ON, Yancey SW, Chanez P; MENSA Investigators. Ortega HG, et al. N Engl J Med. 2014 Sep 25;371(13):1198-207. doi: 10.1056/NEJMoa1403290. Epub 2014 Sep 8. N Engl J Med. 2014. PMID: 25199059 Free article. Clinical Trial.
Benralizumab for the Prevention of COPD Exacerbations.
Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators. Criner GJ, et al. N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20. N Engl J Med. 2019. PMID: 31112385 Clinical Trial.
Motor skill learning requires active central myelination.
McKenzie IA, Ohayon D, Li H, de Faria JP, Emery B, Tohyama K, Richardson WD. McKenzie IA, et al. Among authors: tohyama k. Science. 2014 Oct 17;346(6207):318-22. doi: 10.1126/science.1254960. Science. 2014. PMID: 25324381 Free PMC article.
Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization.
Kaito S, Aoyama K, Oshima M, Tsuchiya A, Miyota M, Yamashita M, Koide S, Nakajima-Takagi Y, Kozuka-Hata H, Oyama M, Yogo T, Yabushita T, Ito R, Ueno M, Hirao A, Tohyama K, Li C, Kawabata KC, Yamaguchi K, Furukawa Y, Kosako H, Yoshimi A, Goyama S, Nannya Y, Ogawa S, Agger K, Helin K, Yamazaki S, Koseki H, Doki N, Harada Y, Harada H, Nishiyama A, Nakanishi M, Iwama A. Kaito S, et al. Among authors: tohyama k. Nat Commun. 2024 Aug 28;15(1):7359. doi: 10.1038/s41467-024-50498-4. Nat Commun. 2024. PMID: 39198387 Free PMC article.
Drug transporters in drug disposition - the year 2022 in review.
Chothe PP, Mitra P, Nakakariya M, Ramsden D, Rotter CJ, Sandoval P, Tohyama K. Chothe PP, et al. Among authors: tohyama k. Drug Metab Rev. 2023 Nov;55(4):343-370. doi: 10.1080/03602532.2023.2252618. Epub 2023 Sep 6. Drug Metab Rev. 2023. PMID: 37644867 Review.
Discovery of a novel series of medium-sized cyclic enteropeptidase inhibitors.
Kikuchi F, Ikeda Z, Kakegawa K, Nishikawa Y, Sasaki S, Fukuda K, Takami K, Banno Y, Nishikawa H, Taya N, Nakahata T, Itono S, Yashiro H, Tsuchimori K, Hiyoshi H, Sasaki M, Tohyama K, Matsumiya K, Ishihara Y, Kawamoto T, Kamaura M, Watanabe M, Kitazaki T, Maekawa T, Sasaki M. Kikuchi F, et al. Among authors: tohyama k. Bioorg Med Chem. 2023 Oct 1;93:117462. doi: 10.1016/j.bmc.2023.117462. Epub 2023 Aug 29. Bioorg Med Chem. 2023. PMID: 37683572 Free article.
Astrocyte-mediated infantile-onset leukoencephalopathy mouse model.
Sugio S, Tohyama K, Oku S, Fujiyoshi K, Yoshimura T, Hikishima K, Yano R, Fukuda T, Nakamura M, Okano H, Watanabe M, Fukata M, Ikenaka K, Tanaka KF. Sugio S, et al. Among authors: tohyama k. Glia. 2017 Jan;65(1):150-168. doi: 10.1002/glia.23084. Epub 2016 Oct 17. Glia. 2017. PMID: 27748972
Novel insights in drug transporter sciences: the year 2021 in review.
Chothe PP, Mitra P, Nakakariya M, Ramsden D, Rotter CJ, Sandoval P, Tohyama K. Chothe PP, et al. Among authors: tohyama k. Drug Metab Rev. 2022 Aug;54(3):299-317. doi: 10.1080/03602532.2022.2094944. Epub 2022 Jul 8. Drug Metab Rev. 2022. PMID: 35762758 Review.
369 results