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1954 1
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2010 3
2011 3
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32 results

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Page 1
In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.
Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS. Lin BL, et al. Among authors: rast g. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161. doi: 10.1073/pnas.1815354116. Epub 2019 Apr 26. Proc Natl Acad Sci U S A. 2019. PMID: 31028142 Free PMC article.
Optimization of bioanalysis of dried blood samples.
Alizadeh EA, Rast G, Cantow C, Schiwon J, Krause F, De Meyer GRY, Guns PJ, Guth BD, Markert M. Alizadeh EA, et al. Among authors: rast g. J Pharmacol Toxicol Methods. 2023 Sep-Oct;123:107296. doi: 10.1016/j.vascn.2023.107296. Epub 2023 Jul 22. J Pharmacol Toxicol Methods. 2023. PMID: 37482323 Free article.
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer.
Kuttruff CA, Fleck M, Carotta S, Arnhof H, Bretschneider T, Dahmann G, Gremel G, Grube A, Handschuh S, Heimann A, Hofmann MH, Impagnatiello MA, Nar H, Rast G, Schaaf O, Schmidt E, Oost T. Kuttruff CA, et al. Among authors: rast g. J Med Chem. 2023 Jul 27;66(14):9376-9400. doi: 10.1021/acs.jmedchem.3c00510. Epub 2023 Jul 14. J Med Chem. 2023. PMID: 37450324
Virtual clinical QT exposure-response studies - A translational computational approach.
Aguado-Sierra J, Dominguez-Gomez P, Amar A, Butakoff C, Leitner M, Schaper S, Kriegl JM, Darpo B, Vazquez M, Rast G. Aguado-Sierra J, et al. Among authors: rast g. J Pharmacol Toxicol Methods. 2024 Mar-Apr;126:107498. doi: 10.1016/j.vascn.2024.107498. Epub 2024 Mar 1. J Pharmacol Toxicol Methods. 2024. PMID: 38432528 Free article.
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.
Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, Del Camino D, Cantin S, D'Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM. Just S, et al. Among authors: rast g. PLoS One. 2018 Jan 31;13(1):e0191225. doi: 10.1371/journal.pone.0191225. eCollection 2018. PLoS One. 2018. PMID: 29385160 Free PMC article.
32 results