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Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Among authors: pickens co. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
Individual target pharmacokinetic/pharmacodynamic attainment rates among meropenem-treated patients admitted to the ICU with hospital-acquired pneumonia.
Rohani R, Scheetz MH, Donnelly HK, Donayre A, Kang M, Diaz E, Dedicatoria K, Hauser AR, Ozer EA, Nozick S, Qi C, Pawlowski AE, Neely MN, Misharin AV, Wunderink RG, Rhodes NJ; NU SCRIPT Study investigators. Rohani R, et al. J Antimicrob Chemother. 2022 Oct 28;77(11):2956-2959. doi: 10.1093/jac/dkac245. J Antimicrob Chemother. 2022. PMID: 35869779 Free PMC article.
Bacterial superinfection pneumonia in SARS-CoV-2 respiratory failure.
Pickens CO, Gao CA, Cuttica M, Smith SB, Pesce L, Grant R, Kang M, Morales-Nebreda L, Bavishi AA, Arnold J, Pawlowski A, Qi C, Budinger GS, Singer BD, Wunderink RG. Pickens CO, et al. medRxiv [Preprint]. 2021 Jan 15:2021.01.12.20248588. doi: 10.1101/2021.01.12.20248588. medRxiv. 2021. Update in: Am J Respir Crit Care Med. 2021 Oct 15;204(8):921-932. doi: 10.1164/rccm.202106-1354OC PMID: 33469593 Free PMC article. Updated. Preprint.
Distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.
Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Nat Immunol. 2024 Sep;25(9):1607-1622. doi: 10.1038/s41590-024-01914-w. Epub 2024 Aug 13. Nat Immunol. 2024. PMID: 39138384
Comparing Nasopharyngeal and BAL SARS-CoV-2 Assays in Respiratory Failure.
Gao CA, Cuttica MJ, Malsin ES, Argento AC, Wunderink RG, Smith SB; NU COVID Investigators. Gao CA, et al. Am J Respir Crit Care Med. 2021 Jan 1;203(1):127-129. doi: 10.1164/rccm.202008-3137LE. Am J Respir Crit Care Med. 2021. PMID: 33125256 Free PMC article. No abstract available.
Bacterial Superinfection Pneumonia in Patients Mechanically Ventilated for COVID-19 Pneumonia.
Pickens CO, Gao CA, Cuttica MJ, Smith SB, Pesce LL, Grant RA, Kang M, Morales-Nebreda L, Bavishi AA, Arnold JM, Pawlowski A, Qi C, Budinger GRS, Singer BD, Wunderink RG; NU COVID Investigators. Pickens CO, et al. Am J Respir Crit Care Med. 2021 Oct 15;204(8):921-932. doi: 10.1164/rccm.202106-1354OC. Am J Respir Crit Care Med. 2021. PMID: 34409924 Free PMC article.
Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith S, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Among authors: pickens co. bioRxiv [Preprint]. 2020 Aug 7:2020.08.05.238188. doi: 10.1101/2020.08.05.238188. bioRxiv. 2020. Update in: Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w PMID: 34013276 Free PMC article. Updated. Preprint.