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Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis.
Kwok AJ, Allcock A, Ferreira RC, Cano-Gamez E, Smee M, Burnham KL, Zurke YX; Emergency Medicine Research Oxford (EMROx); McKechnie S, Mentzer AJ, Monaco C, Udalova IA, Hinds CJ, Todd JA, Davenport EE, Knight JC. Kwok AJ, et al. Nat Immunol. 2023 May;24(5):767-779. doi: 10.1038/s41590-023-01490-5. Epub 2023 Apr 24. Nat Immunol. 2023. PMID: 37095375
Albumin Versus Balanced Crystalloid for the Early Resuscitation of Sepsis: An Open Parallel-Group Randomized Feasibility Trial- The ABC-Sepsis Trial.
Gray AJ, Oatey K, Grahamslaw J, Irvine S, Cafferkey J, Kennel T, Norrie J, Walsh T, Lone N, Horner D, Appelboam A, Hall P, Skipworth RJE, Bell D, Rooney K, Shankar-Hari M, Corfield AR; Albumin, Balanced, and Crystalloid-Sepsis (ABC-Sepsis) Investigators. Gray AJ, et al. Crit Care Med. 2024 Oct 1;52(10):1520-1532. doi: 10.1097/CCM.0000000000006348. Epub 2024 Jun 24. Crit Care Med. 2024. PMID: 38912884 Clinical Trial.