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Year Number of Results
1984 2
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1999 2
2000 3
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2002 1
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111 results

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Page 1
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D, Brunmeir R, Yeap YJ, O'Brien NL, Groet J, Shao X, Havlicek S, Dunn NR, Kvartsberg H, Brinkmalm G, Hithersay R, Startin C, Hamburg S, Phillips M, Pervushin K, Turmaine M, Wallon D, Rovelet-Lecrux A, Soininen H, Volpi E, Martin JE, Foo JN, Becker DL, Rostagno A, Ghiso J, Krsnik Ž, Šimić G, Kostović I, Mitrečić D; LonDownS Consortium; Francis PT, Blennow K, Strydom A, Hardy J, Zetterberg H, Nižetić D. Alić I, et al. Among authors: nizetic d. Mol Psychiatry. 2021 Oct;26(10):5766-5788. doi: 10.1038/s41380-020-0806-5. Epub 2020 Jul 10. Mol Psychiatry. 2021. PMID: 32647257 Free PMC article.
Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels.
Murray A, Gough G, Cindrić A, Vučković F, Koschut D, Borelli V, Petrović DJ, Bekavac A, Plećaš A, Hribljan V, Brunmeir R, Jurić J, Pučić-Baković M, Slana A, Deriš H, Frkatović A, Groet J, O'Brien NL, Chen HY, Yeap YJ, Delom F, Havlicek S, Gammon L, Hamburg S, Startin C, D'Souza H, Mitrečić D, Kero M, Odak L, Krušlin B, Krsnik Ž, Kostović I, Foo JN, Loh YH, Dunn NR, de la Luna S, Spector T, Barišić I, Thomas MSC, Strydom A, Franceschi C, Lauc G, Krištić J, Alić I, Nižetić D. Murray A, et al. Among authors: nizetic d. EBioMedicine. 2023 Aug;94:104692. doi: 10.1016/j.ebiom.2023.104692. Epub 2023 Jul 12. EBioMedicine. 2023. PMID: 37451904 Free PMC article.
Cerebral organoids with chromosome 21 trisomy secrete Alzheimer's disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy.
Fertan E, Böken D, Murray A, Danial JSH, Lam JYL, Wu Y, Goh PA, Alić I, Cheetham MR, Lobanova E, Zhang YP, Nižetić D, Klenerman D. Fertan E, et al. Among authors: nizetic d. Mol Psychiatry. 2024 Feb;29(2):369-386. doi: 10.1038/s41380-023-02333-3. Epub 2023 Dec 15. Mol Psychiatry. 2024. PMID: 38102482 Free PMC article.
Modeling Down syndrome in cells: From stem cells to organoids.
Gough G, O'Brien NL, Alic I, Goh PA, Yeap YJ, Groet J, Nizetic D, Murray A. Gough G, et al. Among authors: nizetic d. Prog Brain Res. 2020;251:55-90. doi: 10.1016/bs.pbr.2019.10.003. Epub 2019 Nov 20. Prog Brain Res. 2020. PMID: 32057312 Review.
The importance of understanding individual differences in Down syndrome.
Karmiloff-Smith A, Al-Janabi T, D'Souza H, Groet J, Massand E, Mok K, Startin C, Fisher E, Hardy J, Nizetic D, Tybulewicz V, Strydom A. Karmiloff-Smith A, et al. Among authors: nizetic d. F1000Res. 2016 Mar 23;5:F1000 Faculty Rev-389. doi: 10.12688/f1000research.7506.1. eCollection 2016. F1000Res. 2016. PMID: 27019699 Free PMC article. Review.
Intracerebral haemorrhage in Down syndrome: protected or predisposed?
Buss L, Fisher E, Hardy J, Nizetic D, Groet J, Pulford L, Strydom A. Buss L, et al. Among authors: nizetic d. F1000Res. 2016 May 12;5:F1000 Faculty Rev-876. doi: 10.12688/f1000research.7819.1. eCollection 2016. F1000Res. 2016. PMID: 27239286 Free PMC article. Review.
Translating molecular advances in Down syndrome and Fragile X syndrome into therapies.
Faundez V, De Toma I, Bardoni B, Bartesaghi R, Nizetic D, de la Torre R, Cohen Kadosh R, Herault Y, Dierssen M, Potier MC; Down Syndrome and Other Genetic Developmental Disorders ECNP Network. Faundez V, et al. Among authors: nizetic d. Eur Neuropsychopharmacol. 2018 Jun;28(6):675-690. doi: 10.1016/j.euroneuro.2018.03.006. Epub 2018 Jun 7. Eur Neuropsychopharmacol. 2018. PMID: 29887288 Review.
A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome.
Wiseman FK, Al-Janabi T, Hardy J, Karmiloff-Smith A, Nizetic D, Tybulewicz VL, Fisher EM, Strydom A. Wiseman FK, et al. Among authors: nizetic d. Nat Rev Neurosci. 2015 Sep;16(9):564-74. doi: 10.1038/nrn3983. Epub 2015 Aug 5. Nat Rev Neurosci. 2015. PMID: 26243569 Free PMC article. Review.
111 results