SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence.
Gioia U, Tavella S, Martínez-Orellana P, Cicio G, Colliva A, Ceccon M, Cabrini M, Henriques AC, Fumagalli V, Paldino A, Presot E, Rajasekharan S, Iacomino N, Pisati F, Matti V, Sepe S, Conte MI, Barozzi S, Lavagnino Z, Carletti T, Volpe MC, Cavalcante P, Iannacone M, Rampazzo C, Bussani R, Tripodo C, Zacchigna S, Marcello A, d'Adda di Fagagna F.
Gioia U, et al. Among authors: martinez orellana p.
Nat Cell Biol. 2023 Apr;25(4):550-564. doi: 10.1038/s41556-023-01096-x. Epub 2023 Mar 9.
Nat Cell Biol. 2023.
PMID: 36894671
Free PMC article.