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Page 1
Showing results for china sk
Search for Chinka SK instead (1 results)
Safety and efficacy of rimegepant orally disintegrating tablet for the acute treatment of migraine in China and South Korea: a phase 3, double-blind, randomised, placebo-controlled trial.
Yu S, Kim BK, Guo A, Kim MH, Zhang M, Wang Z, Liu J, Moon HS, Tan G, Yang Q, McGrath D, Hanna M, Stock DA, Gao Y, Croop R, Lu Z. Yu S, et al. Lancet Neurol. 2023 Jun;22(6):476-484. doi: 10.1016/S1474-4422(23)00126-6. Lancet Neurol. 2023. PMID: 37210098 Clinical Trial.
BACKGROUND: No acute treatments targeting calcitonin gene-related peptide (CGRP) have been approved for use in China or South Korea. We aimed to compare the efficacy and safety of rimegepant-an orally administered small molecule CGRP antagonist-with placebo in the acute tr …
BACKGROUND: No acute treatments targeting calcitonin gene-related peptide (CGRP) have been approved for use in China or South Korea. …
The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic.
Worobey M, Levy JI, Malpica Serrano L, Crits-Christoph A, Pekar JE, Goldstein SA, Rasmussen AL, Kraemer MUG, Newman C, Koopmans MPG, Suchard MA, Wertheim JO, Lemey P, Robertson DL, Garry RF, Holmes EC, Rambaut A, Andersen KG. Worobey M, et al. Science. 2022 Aug 26;377(6609):951-959. doi: 10.1126/science.abp8715. Epub 2022 Jul 26. Science. 2022. PMID: 35881010 Free PMC article.
The Huanan Seafood Wholesale Market in Wuhan, China, was identified as a likely source of cases in early reports, but later this conclusion became controversial. ...Although there is insufficient evidence to define upstream events, and exact circumstances remain obscure, o …
The Huanan Seafood Wholesale Market in Wuhan, China, was identified as a likely source of cases in early reports, but later this conc …
DIALIZE China: A Phase IIIb, Randomized, Placebo-Controlled Study to Reduce Predialysis Hyperkalemia With Sodium Zirconium Cyclosilicate in Chinese Patients.
Ni Z, Lu R, Xu X, Bian X, Zhou Z, Yang J, Luo Q, Chen M, Chen C, Sun X, Yu L, He Q, Jiang H, Yuan W, Li Y, Zhou R, Wang J, Zhang X, Zuo L, Meng X, Chang Z, Zhao J, Wessman P, Xiang P; DIALIZE China Study Group. Ni Z, et al. Clin Ther. 2023 Jul;45(7):633-642. doi: 10.1016/j.clinthera.2023.04.014. Epub 2023 Jun 27. Clin Ther. 2023. PMID: 37385905 Free article. Clinical Trial.
METHODS: In the double-blind, Phase IIIb DIALIZE China study, Chinese adults with kidney failure and predialysis hyperkalemia (predialysis serum potassium [sK(+)] concentration >5.4 mmol/L after the long interdialytic interval [LIDI] and >5.0 mmol/L after 1 sh …
METHODS: In the double-blind, Phase IIIb DIALIZE China study, Chinese adults with kidney failure and predialysis hyperkalemia (predia …
Modulation of SK Channels: Insight Into Therapeutics of Atrial Fibrillation.
Qi MM, Qian LL, Wang RX. Qi MM, et al. Heart Lung Circ. 2021 Aug;30(8):1130-1139. doi: 10.1016/j.hlc.2021.01.009. Epub 2021 Feb 26. Heart Lung Circ. 2021. PMID: 33642173 Free article. Review.
The small conductance Ca(2+)-activated K(+) channels (SK channels) are dependent on intracellular Ca(2+) concentrations, which tightly integrate with membrane potential. ...This review aimed to illustrate the characteristics and function of SK channels. Moreover, it …
The small conductance Ca(2+)-activated K(+) channels (SK channels) are dependent on intracellular Ca(2+) concentrations, which tightl …
Small-conductance calcium-activated potassium channels in the heart: expression, regulation and pathological implications.
Liu T, Li T, Xu D, Wang Y, Zhou Y, Wan J, Huang CL, Tan X. Liu T, et al. Philos Trans R Soc Lond B Biol Sci. 2023 Jun 19;378(1879):20220171. doi: 10.1098/rstb.2022.0171. Epub 2023 May 1. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 37122223 Free PMC article. Review.
All SK channels, particularly SK2 channels, are expressed in atrial, ventricular and conducting system cardiomyocytes. ...SK function also depends upon complex trafficking and expression processes and associations with other ion channels or subunits from different …
All SK channels, particularly SK2 channels, are expressed in atrial, ventricular and conducting system cardiomyocytes. ...SK f …
Targeting HNRNPA2B1 inhibits enterovirus 71 replication in SK-N-SH cells.
Wu J, Lu J, Mao L, Xu M, Dai L, Wang Y. Wu J, et al. Virus Res. 2023 Oct 15;336:199224. doi: 10.1016/j.virusres.2023.199224. Epub 2023 Sep 16. Virus Res. 2023. PMID: 37716669 Free PMC article.
OBJECTIVE: To investigate the effect of heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) on the replication of enterovirus 71 (EV-71) in SK-N-SH cells. METHODS: The mRNA and protein expression of HNRNPA2B1 in SK-N-SH cells were detected by real-time quantita …
OBJECTIVE: To investigate the effect of heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) on the replication of enterovirus 71 (EV-71 …
Prevention of STAT3-related pathway in SK-N-SH cells by natural product astaxanthin.
Sun SQ, Du FX, Zhang LH, Hao-Shi, Gu FY, Deng YL, Ji YZ. Sun SQ, et al. BMC Complement Med Ther. 2023 Nov 29;23(1):430. doi: 10.1186/s12906-023-04267-3. BMC Complement Med Ther. 2023. PMID: 38031104 Free PMC article.
In this study, we investigated whether astaxanthin could exert antitumor effects in the SK-N-SH neuroblastoma cancer cell line. METHOD: MTT and colony formation assays were used to determine the effect of astaxanthin on the proliferation and colony formation of SK-N …
In this study, we investigated whether astaxanthin could exert antitumor effects in the SK-N-SH neuroblastoma cancer cell line. METHO …
European Society of Anaesthesiology and Intensive Care consensus document on sustainability: 4 scopes to achieve a more sustainable practice.
Gonzalez-Pizarro P, Brazzi L, Koch S, Trinks A, Muret J, Sperna Weiland N, Jovanovic G, Cortegiani A, Fernandes TD, Kranke P, Malisiova A, McConnell P, Misquita L, Romero CS, Bilotta F, De Robertis E, Buhre W; Sustainability National Representatives. Gonzalez-Pizarro P, et al. Eur J Anaesthesiol. 2024 Apr 1;41(4):260-277. doi: 10.1097/EJA.0000000000001942. Epub 2024 Jan 18. Eur J Anaesthesiol. 2024. PMID: 38235604
The carbon footprint of clinical practice accounts for 4.7% of European greenhouse gas emissions, with the European Union ranking as the third largest contributor to the global healthcare industry's carbon footprint, after the United States and China. Recognising the impor …
The carbon footprint of clinical practice accounts for 4.7% of European greenhouse gas emissions, with the European Union ranking as the thi …
Inhibition of SK Channels in VTA Affects Dopaminergic Neurons to Improve the Depression-Like Behaviors of Post-Stroke Depression Rats.
Wang A, Zhou Y, Chen H, Jin J, Mao Y, Tao S, Qiu T. Wang A, et al. Neuropsychiatr Dis Treat. 2023 Oct 9;19:2127-2139. doi: 10.2147/NDT.S426091. eCollection 2023. Neuropsychiatr Dis Treat. 2023. PMID: 37840624 Free PMC article.
PATIENTS AND METHODS: Four groups of Sprague-Dawley rats were randomly divided: Control, PSD, SK channel inhibitor (apamin) and SK channel activator (CyPPA) groups. In both control and CyPPA groups, sham surgery was performed. ...And depression-related behavior is i …
PATIENTS AND METHODS: Four groups of Sprague-Dawley rats were randomly divided: Control, PSD, SK channel inhibitor (apamin) and SK
Prevalence and Procedural Risk of Intracranial Atherosclerotic Stenosis Coexisting With Unruptured Intracranial Aneurysm.
Yin Z, Zhang Q, Zhao Y, Lu J, Ge P, Xie H, Wu D, Yu S, Kang S, Zhang Q, Zhang Y, Zhang D, Zhao J, Liu X. Yin Z, et al. Stroke. 2023 Jun;54(6):1484-1493. doi: 10.1161/STROKEAHA.122.041553. Epub 2023 May 4. Stroke. 2023. PMID: 37139814 Clinical Trial.
METHODS: Based on the CAIASA study (Coexistence of Atherosclerotic Intracranial Arterial Stenosis With Intracranial Aneurysms), we prospectively included patients undergoing treatment procedures for UIAs from October 2015 to December 2020 at Beijing Tiantan Hospital, China
METHODS: Based on the CAIASA study (Coexistence of Atherosclerotic Intracranial Arterial Stenosis With Intracranial Aneurysms), we prospecti …
5,131 results