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2023 7
2024 6

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Human microglia maturation is underpinned by specific gene regulatory networks.
Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, Kim R, Schafer D, Ramirez G, Challacombe J, Anavim SA, Johnson A, Gupta M, Glass IA; Birth Defects Research Laboratory; Levy ML, Haim SB, Gonda DD, Laurent L, Hughes JF, Page DC, Blurton-Jones M, Glass CK, Coufal NG. Han CZ, et al. Immunity. 2023 Sep 12;56(9):2152-2171.e13. doi: 10.1016/j.immuni.2023.07.016. Epub 2023 Aug 14. Immunity. 2023. PMID: 37582369 Free PMC article.
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.
Shen M, Sirois CL, Guo Y, Li M, Dong Q, Méndez-Albelo NM, Gao Y, Khullar S, Kissel L, Sandoval SO, Wolkoff NE, Huang SX, Xu Z, Bryan JE, Contractor AM, Korabelnikov T, Glass IA, Doherty D; Birth Defects Research Laboratory; Levine JE, Sousa AMM, Chang Q, Bhattacharyya A, Wang D, Werling DM, Zhao X. Shen M, et al. Neuron. 2023 Dec 20;111(24):3988-4005.e11. doi: 10.1016/j.neuron.2023.09.014. Epub 2023 Oct 10. Neuron. 2023. PMID: 37820724
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia.
Dorion MF, Yaqubi M, Senkevich K, Kieran NW, MacDonald A, Chen CXQ, Luo W, Wallis A, Shlaifer I, Hall JA, Dudley RWR, Glass IA; Birth Defects Research Laboratory; Stratton JA, Fon EA, Bartels T, Antel JP, Gan-Or Z, Durcan TM, Healy LM. Dorion MF, et al. Brain. 2024 Feb 1;147(2):427-443. doi: 10.1093/brain/awad298. Brain. 2024. PMID: 37671615 Free PMC article.
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway.
Guo Y, Shen M, Dong Q, Méndez-Albelo NM, Huang SX, Sirois CL, Le J, Li M, Jarzembowski ED, Schoeller KA, Stockton ME, Horner VL, Sousa AMM, Gao Y; Birth Defects Research Laboratory; Levine JE, Wang D, Chang Q, Zhao X. Guo Y, et al. Nat Commun. 2023 Jun 26;14(1):3801. doi: 10.1038/s41467-023-39337-0. Nat Commun. 2023. PMID: 37365192 Free PMC article.
A Trisomy 21 Lung Cell Atlas.
Bhattacharya S, Cherry C, Deutsch G; Birth Defects Research Laboratory (BDRL); Glass IA, Mariani TJ, Alam DA, Danopoulos S. Bhattacharya S, et al. bioRxiv [Preprint]. 2023 Apr 3:2023.03.30.534839. doi: 10.1101/2023.03.30.534839. bioRxiv. 2023. PMID: 37066313 Free PMC article. Preprint.
Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues.
Chambers CZ, Soo GL, Engel AL; Birth Defects Research Laboratory (BDRL); Glass IA, Frassetto A, Martini PGV, Cherry TJ. Chambers CZ, et al. bioRxiv [Preprint]. 2023 Jul 13:2023.07.13.548758. doi: 10.1101/2023.07.13.548758. bioRxiv. 2023. Update in: Transl Vis Sci Technol. 2024 Jul 1;13(7):7. doi: 10.1167/tvst.13.7.7 PMID: 37502987 Free PMC article. Updated. Preprint.
A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa.
Yang Y, McCullough CG, Seninge L, Guo L, Kwon WJ, Zhang Y, Li NY, Gaddam S, Pan C, Zhen H, Torkelson J, Glass IA; Birth Defects Research Laboratory; Charville G, Que J, Stuart J, Ding H, Oro A. Yang Y, et al. bioRxiv [Preprint]. 2023 Oct 26:2023.10.24.563664. doi: 10.1101/2023.10.24.563664. bioRxiv. 2023. PMID: 37961271 Free PMC article. Preprint.
Multi-omics identification of extracellular components of the fetal monkey and human neocortex.
Vilicich F, Vettiatil D, Kattapong-Graber S, Nawsheen N, Patel N, Quezada A, Gurney E, Smith E, Nelson H, Pesci S, Atrio J, Moreno N, Jones A, Murphy M, Benfield N, Hennebold J, Solanky N, Lisgo S, Glass I; Birth Defects Research Laboratory (BDRL); Sidoli S. Vilicich F, et al. bioRxiv [Preprint]. 2024 Sep 26:2024.09.25.615077. doi: 10.1101/2024.09.25.615077. bioRxiv. 2024. PMID: 39386730 Free PMC article. Preprint.
12 results