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Negative Hyperselection of Resistance Mutations for Panitumumab Maintenance in RAS Wild-Type Metastatic Colorectal Cancer (PanaMa Phase II Trial, AIO KRK 0212).
Clin Cancer Res. 2024 Apr 1;30(7):1256-1263. doi: 10.1158/1078-0432.CCR-23-3023.
Clin Cancer Res. 2024.
PMID: 38289994
Clinical Trial.
A combinatorially complete epistatic fitness landscape in an enzyme active site.
Johnston KE, Almhjell PJ, Watkins-Dulaney EJ, Liu G, Porter NJ, Yang J, Arnold FH.
Johnston KE, et al.
Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2400439121. doi: 10.1073/pnas.2400439121. Epub 2024 Jul 29.
Proc Natl Acad Sci U S A. 2024.
PMID: 39074291
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