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Page 1
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.
Steklov M, Pandolfi S, Baietti MF, Batiuk A, Carai P, Najm P, Zhang M, Jang H, Renzi F, Cai Y, Abbasi Asbagh L, Pastor T, De Troyer M, Simicek M, Radaelli E, Brems H, Legius E, Tavernier J, Gevaert K, Impens F, Messiaen L, Nussinov R, Heymans S, Eyckerman S, Sablina AA. Steklov M, et al. Science. 2018 Dec 7;362(6419):1177-1182. doi: 10.1126/science.aap7607. Epub 2018 Nov 15. Science. 2018. PMID: 30442762 Free PMC article.
Inhibition of Nonfunctional Ras.
Nussinov R, Jang H, Gursoy A, Keskin O, Gaponenko V. Nussinov R, et al. Cell Chem Biol. 2021 Feb 18;28(2):121-133. doi: 10.1016/j.chembiol.2020.12.012. Epub 2021 Jan 12. Cell Chem Biol. 2021. PMID: 33440168 Free PMC article. Review.
Drugging multiple same-allele driver mutations in cancer.
Nussinov R, Zhang M, Maloney R, Jang H. Nussinov R, et al. Expert Opin Drug Discov. 2021 Aug;16(8):823-828. doi: 10.1080/17460441.2021.1905628. Epub 2021 Mar 26. Expert Opin Drug Discov. 2021. PMID: 33769165 Free PMC article. No abstract available.
A New View of Activating Mutations in Cancer.
Nussinov R, Tsai CJ, Jang H. Nussinov R, et al. Cancer Res. 2022 Nov 15;82(22):4114-4123. doi: 10.1158/0008-5472.CAN-22-2125. Cancer Res. 2022. PMID: 36069825 Free PMC article.
Antimicrobial properties of amyloid peptides.
Kagan BL, Jang H, Capone R, Teran Arce F, Ramachandran S, Lal R, Nussinov R. Kagan BL, et al. Mol Pharm. 2012 Apr 2;9(4):708-17. doi: 10.1021/mp200419b. Epub 2011 Nov 29. Mol Pharm. 2012. PMID: 22081976 Free PMC article. Review.
49 results