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63 results

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Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, Zhang B, Gaiteri C, Bennett DA, Gearing M, Wingo TS, Wingo AP, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Nat Neurosci. 2022 Feb;25(2):213-225. doi: 10.1038/s41593-021-00999-y. Epub 2022 Feb 3. Nat Neurosci. 2022. PMID: 35115731 Free PMC article.
Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease.
Tsai AP, Dong C, Lin PB, Oblak AL, Viana Di Prisco G, Wang N, Hajicek N, Carr AJ, Lendy EK, Hahn O, Atkins M, Foltz AG, Patel J, Xu G, Moutinho M, Sondek J, Zhang Q, Mesecar AD, Liu Y, Atwood BK, Wyss-Coray T, Nho K, Bissel SJ, Lamb BT, Landreth GE. Tsai AP, et al. Immunity. 2023 Sep 12;56(9):2121-2136.e6. doi: 10.1016/j.immuni.2023.08.008. Epub 2023 Sep 1. Immunity. 2023. PMID: 37659412 Free PMC article.
Cross-species comparative hippocampal transcriptomics in Alzheimer's disease.
De Bastiani MA, Bellaver B, Carello-Collar G, Zimmermann M, Kunach P, Lima-Filho RAS, Forner S, Martini AC, Pascoal TA, Lourenco MV, Rosa-Neto P, Zimmer ER. De Bastiani MA, et al. iScience. 2023 Dec 7;27(1):108671. doi: 10.1016/j.isci.2023.108671. eCollection 2024 Jan 19. iScience. 2023. PMID: 38292167 Free PMC article.
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Sasner M, Preuss C, Pandey RS, Uyar A, Garceau D, Kotredes KP, Williams H, Oblak AL, Lin PB, Perkins B, Soni D, Ingraham C, Lee-Gosselin A, Lamb BT, Howell GR, Carter GW. Sasner M, et al. Alzheimers Dement. 2024 Jul;20(7):4970-4984. doi: 10.1002/alz.13840. Epub 2024 Apr 30. Alzheimers Dement. 2024. PMID: 38687251 Free PMC article.
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Sasner M, Preuss C, Pandey RS, Uyar A, Garceau D, Kotredes KP, Williams H, Oblak AL, Lin PB, Perkins B, Soni D, Ingraham C, Lee-Gosselin A, Lamb BT, Howell GR, Carter GW. Sasner M, et al. bioRxiv [Preprint]. 2023 Dec 24:2023.12.21.572849. doi: 10.1101/2023.12.21.572849. bioRxiv. 2023. Update in: Alzheimers Dement. 2024 Jul;20(7):4970-4984. doi: 10.1002/alz.13840. PMID: 38187758 Free PMC article. Updated. Preprint.
Characterizing Molecular and Synaptic Signatures in mouse models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology.
Kotredes KP, Pandey RS, Persohn S, Elderidge K, Burton CP, Miner EW, Haynes KA, Santos DFS, Williams SP, Heaton N, Ingraham CM, Lloyd C, Garceau D, O'Rourke R, Herrick S, Rangel-Barajas C, Maharjan S, Wang N, Sasner M, Lamb BT, Territo PR, Sukoff Rizzo SJ, Carter GW, Howell GR, Oblak AL. Kotredes KP, et al. bioRxiv [Preprint]. 2023 Dec 20:2023.12.19.571985. doi: 10.1101/2023.12.19.571985. bioRxiv. 2023. Update in: Alzheimers Dement. 2024 Jun;20(6):4126-4146. doi: 10.1002/alz.13828. PMID: 38187716 Free PMC article. Updated. Preprint.
63 results