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Notch4 reveals a novel mechanism regulating Notch signal transduction.
James AC, Szot JO, Iyer K, Major JA, Pursglove SE, Chapman G, Dunwoodie SL. James AC, et al. Biochim Biophys Acta. 2014 Jul;1843(7):1272-84. doi: 10.1016/j.bbamcr.2014.03.015. Epub 2014 Mar 22. Biochim Biophys Acta. 2014. PMID: 24667410 Free article.
ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling.
Handschuh K, Feenstra J, Koss M, Ferretti E, Risolino M, Zewdu R, Sahai MA, Bénazet JD, Peng XP, Depew MJ, Quintana L, Sharpe J, Wang B, Alcorn H, Rivi R, Butcher S, Manak JR, Vaccari T, Weinstein H, Anderson KV, Lacy E, Selleri L. Handschuh K, et al. Cell Rep. 2014 Oct 23;9(2):674-87. doi: 10.1016/j.celrep.2014.09.019. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373905 Free PMC article.
No obvious phenotypic abnormalities in mice lacking the Pate4 gene.
Heckt T, Keller J, Reusch R, Hartmann K, Krasemann S, Hermans-Borgmeyer I, Amling M, Schinke T. Heckt T, et al. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1069-74. doi: 10.1016/j.bbrc.2015.12.104. Epub 2015 Dec 28. Biochem Biophys Res Commun. 2016. PMID: 26731031
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