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Page 1
The NIH Somatic Cell Genome Editing program.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. Saha K, et al. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828315 Free PMC article. Review.
Nonhuman Primates in Translational Research.
Tarantal AF, Noctor SC, Hartigan-O'Connor DJ. Tarantal AF, et al. Annu Rev Anim Biosci. 2022 Feb 15;10:441-468. doi: 10.1146/annurev-animal-021419-083813. Annu Rev Anim Biosci. 2022. PMID: 35167321 Free PMC article. Review.
Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo.
Kulhankova K, Traore S, Cheng X, Benk-Fortin H, Hallée S, Harvey M, Roberge J, Couture F, Kohli S, Gross TJ, Meyerholz DK, Rettig GR, Thommandru B, Kurgan G, Wohlford-Lenane C, Hartigan-O'Connor DJ, Yates BP, Newby GA, Liu DR, Tarantal AF, Guay D, McCray PB Jr. Kulhankova K, et al. Nat Commun. 2023 Dec 5;14(1):8051. doi: 10.1038/s41467-023-43904-w. Nat Commun. 2023. PMID: 38052872 Free PMC article.
Translational Utility of the Nonhuman Primate Model.
Tarantal AF, Hartigan-O'Connor DJ, Noctor SC. Tarantal AF, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 May;7(5):491-497. doi: 10.1016/j.bpsc.2022.03.001. Epub 2022 Mar 10. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022. PMID: 35283343 Free PMC article. Review.
Systematic multi-trait AAV capsid engineering for efficient gene delivery.
Eid FE, Chen AT, Chan KY, Huang Q, Zheng Q, Tobey IG, Pacouret S, Brauer PP, Keyes C, Powell M, Johnston J, Zhao B, Lage K, Tarantal AF, Chan YA, Deverman BE. Eid FE, et al. Nat Commun. 2024 Aug 4;15(1):6602. doi: 10.1038/s41467-024-50555-y. Nat Commun. 2024. PMID: 39097583 Free PMC article.
The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota.
Stevens J, Steinmeyer S, Bonfield M, Peterson L, Wang T, Gray J, Lewkowich I, Xu Y, Du Y, Guo M, Wynn JL, Zacharias W, Salomonis N, Miller L, Chougnet C, O'Connor DH, Deshmukh H. Stevens J, et al. Sci Transl Med. 2022 Jun 15;14(649):eabl3981. doi: 10.1126/scitranslmed.abl3981. Epub 2022 Jun 15. Sci Transl Med. 2022. PMID: 35704600 Free PMC article.
Shuttle Peptide Delivers Base Editor RNPs to Rhesus Monkey Airway Epithelial Cells In Vivo.
Kulhankova K, Traore S, Cheng X, Benk-Fortin H, Hallée S, Harvey M, Roberge J, Couture F, Gross T, Newby G, Liu D, Tarantal A, Guay D, McCray P Jr. Kulhankova K, et al. Res Sq [Preprint]. 2023 Feb 17:rs.3.rs-2540755. doi: 10.21203/rs.3.rs-2540755/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Dec 5;14(1):8051. doi: 10.1038/s41467-023-43904-w PMID: 36824928 Free PMC article. Updated. Preprint.
Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET).
Rossano S, Toyonaga T, Berg E, Lorence I, Fowles K, Nabulsi N, Ropchan J, Li S, Ye Y, Felchner Z, Kukis D, Huang Y, Benveniste H, Tarantal AF, Groman S, Carson RE. Rossano S, et al. Eur J Nucl Med Mol Imaging. 2022 Sep;49(11):3679-3691. doi: 10.1007/s00259-022-05825-6. Epub 2022 May 28. Eur J Nucl Med Mol Imaging. 2022. PMID: 35633376 Free PMC article.