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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.
Molina JJ, Kohler KN, Gager C, Andersen MJ, Wongso E, Lucas ER, Paik A, Xu W, Donahue DL, Bergeron K, Klim A, Caparon MG, Hultgren SJ, Desai A, Ploplis VA, Flick MJ, Castellino FJ, Flores-Mireles AL. Molina JJ, et al. Nat Commun. 2024 Mar 27;15(1):2704. doi: 10.1038/s41467-024-46974-6. Nat Commun. 2024. PMID: 38538626 Free PMC article.
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.
Molina JJ, Kohler KN, Gager C, Andersen MJ, Wongso E, Lucas ER, Paik A, Xu W, Donahue DL, Bergeron K, Klim A, Caparon MG, Hultgren SJ, Desai A, Ploplis VA, Flick MJ, Castellino FJ, Flores-Mireles AL. Molina JJ, et al. Res Sq [Preprint]. 2023 Sep 15:rs.3.rs-3263501. doi: 10.21203/rs.3.rs-3263501/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 27;15(1):2704. doi: 10.1038/s41467-024-46974-6. PMID: 37790429 Free PMC article. Updated. Preprint.
Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections.
Tamadonfar KO, Di Venanzio G, Pinkner JS, Dodson KW, Kalas V, Zimmerman MI, Bazan Villicana J, Bowman GR, Feldman MF, Hultgren SJ. Tamadonfar KO, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212694120. doi: 10.1073/pnas.2212694120. Epub 2023 Jan 18. Proc Natl Acad Sci U S A. 2023. PMID: 36652481 Free PMC article.
Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics.
Nye TM, Tükenmez H, Singh P, Flores-Mireles AL, Obernuefemann CLP, Pinkner JS, Sarkar S, Bonde M, Lindgren AEG, Dodson KW, Johansson J, Almqvist F, Caparon MG, Hultgren SJ. Nye TM, et al. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2210912119. doi: 10.1073/pnas.2210912119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36252016 Free PMC article.
Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection.
Zou Z, Obernuefemann CLP, Singh P, Pinkner JS, Xu W, Nye TM, Dodson KW, Almqvist F, Hultgren SJ, Caparon MG. Zou Z, et al. bioRxiv [Preprint]. 2024 Jan 3:2024.01.02.573960. doi: 10.1101/2024.01.02.573960. bioRxiv. 2024. Update in: Sci Adv. 2024 Aug 2;10(31):eadn7979. doi: 10.1126/sciadv.adn7979. PMID: 38260261 Free PMC article. Updated. Preprint.
16 results