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Can we mimic skeletal muscles for novel drug discovery?
Broer T, Khodabukus A, Bursac N. Broer T, et al. Expert Opin Drug Discov. 2020 Jun;15(6):643-645. doi: 10.1080/17460441.2020.1736031. Epub 2020 Mar 3. Expert Opin Drug Discov. 2020. PMID: 32122176 Free PMC article. No abstract available.
Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models.
Hakim CH, Kumar SRP, Pérez-López DO, Wasala NB, Zhang D, Yue Y, Teixeira J, Pan X, Zhang K, Million ED, Nelson CE, Metzger S, Han J, Louderman JA, Schmidt F, Feng F, Grimm D, Smith BF, Yao G, Yang NN, Gersbach CA, Chen SJ, Herzog RW, Duan D. Hakim CH, et al. Nat Commun. 2021 Nov 24;12(1):6769. doi: 10.1038/s41467-021-26830-7. Nat Commun. 2021. PMID: 34819506 Free PMC article.
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