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An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish.
Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. Zou J, et al. Elife. 2015 Oct 16;4:e09406. doi: 10.7554/eLife.09406. Elife. 2015. PMID: 26473617 Free PMC article.
Prioritizing causal disease genes using unbiased genomic features.
Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP. Deo RC, et al. Genome Biol. 2014 Dec 3;15(12):534. doi: 10.1186/s13059-014-0534-8. Genome Biol. 2014. PMID: 25633252 Free PMC article.