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Arginase 1 is a key driver of immune suppression in pancreatic cancer.
Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, Carpenter E, Zhang Y, Halbrook CJ, Lyssiotis CA, Pasca di Magliano M. Menjivar RE, et al. Elife. 2023 Feb 2;12:e80721. doi: 10.7554/eLife.80721. Elife. 2023. PMID: 36727849 Free PMC article.
Pancreatic cancer: Advances and challenges.
Halbrook CJ, Lyssiotis CA, Pasca di Magliano M, Maitra A. Halbrook CJ, et al. Cell. 2023 Apr 13;186(8):1729-1754. doi: 10.1016/j.cell.2023.02.014. Cell. 2023. PMID: 37059070 Free PMC article. Review.
Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth.
Donahue KL, Watkoske HR, Kadiyala P, Du W, Brown K, Scales MK, Elhossiny AM, Espinoza CE, Lasse Opsahl EL, Griffith BD, Wen Y, Sun L, Velez-Delgado A, Renollet NM, Morales J, Nedzesky NM, Baliira RK, Menjivar RE, Medina-Cabrera PI, Rao A, Allen B, Shi J, Frankel TL, Carpenter ES, Bednar F, Zhang Y, Pasca di Magliano M. Donahue KL, et al. Cancer Discov. 2024 Oct 4;14(10):1964-1989. doi: 10.1158/2159-8290.CD-24-0100. Cancer Discov. 2024. PMID: 38958646 Free PMC article.
ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma.
Benitz S, Steep A, Nasser MM, Preall J, Mahajan UM, McQuithey H, Loveless I, Davis ET, Wen HJ, Long DW, Metzler T, Zwernik S, Louw M, Rempinski D, Salas-Escabillas DJ, Brender SM, Song L, Huang L, Theisen BK, Zhang Z, Steele NG, Regel I, Bednar F, Crawford HC. Benitz S, et al. Cancer Discov. 2024 Nov 1;14(11):2162-2182. doi: 10.1158/2159-8290.CD-24-0137. Cancer Discov. 2024. PMID: 38975886 Free PMC article.
ROR2 regulates cellular plasticity in pancreatic neoplasia and adenocarcinoma.
Benitz S, Steep A, Nasser M, Preall J, Mahajan UM, McQuithey H, Loveless I, Davis ET, Wen HJ, Long DW, Metzler T, Zwernik S, Louw M, Rempinski D, Salas-Escabillas D, Brender S, Song L, Huang L, Zhang Z, Steele NG, Regel I, Bednar F, Crawford HC. Benitz S, et al. bioRxiv [Preprint]. 2024 Jan 16:2023.12.13.571566. doi: 10.1101/2023.12.13.571566. bioRxiv. 2024. Update in: Cancer Discov. 2024 Nov 1;14(11):2162-2182. doi: 10.1158/2159-8290.CD-24-0137. PMID: 38168289 Free PMC article. Updated. Preprint.
Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions.
Carpenter ES, Elhossiny AM, Kadiyala P, Li J, McGue J, Griffith BD, Zhang Y, Edwards J, Nelson S, Lima F, Donahue KL, Du W, Bischoff AC, Alomari D, Watkoske HR, Mattea M, The S, Espinoza CE, Barrett M, Sonnenday CJ, Olden N, Chen CT, Peterson N, Gunchick V, Sahai V, Rao A, Bednar F, Shi J, Frankel TL, Pasca di Magliano M. Carpenter ES, et al. Cancer Discov. 2023 Jun 2;13(6):1324-1345. doi: 10.1158/2159-8290.CD-23-0013. Cancer Discov. 2023. PMID: 37021392 Free PMC article.
KRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment.
Carpenter ES, Kadiyala P, Elhossiny AM, Kemp SB, Li J, Steele NG, Nicolle R, Nwosu ZC, Freeman J, Dai H, Paglia D, Du W, Donahue K, Morales J, Medina-Cabrera PI, Bonilla ME, Harris L, The S, Gunchick V, Peterson N, Brown K, Mattea M, Espinoza CE, McGue J, Kabala SM, Baliira RK, Renollet NM, Mooney AG, Liu J, Bhalla S, Farida JP, Ko C, Machicado JD, Kwon RS, Wamsteker EJ, Schulman A, Anderson MA, Law R, Prabhu A, Coulombe PA, Rao A, Frankel TL, Bednar F, Shi J, Sahai V, Pasca Di Magliano M. Carpenter ES, et al. Clin Cancer Res. 2024 Jun 3;30(11):2497-2513. doi: 10.1158/1078-0432.CCR-23-1421. Clin Cancer Res. 2024. PMID: 37851080 Free PMC article.
14 results