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Year Number of Results
2017 3
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Page 1
An expanded universe of cancer targets.
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network. Hahn WC, et al. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Cell. 2021. PMID: 33667368 Free PMC article. Review.
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.
Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I; Cancer Genome Atlas Research Network; Monnat RJ Jr, Xiao Y, Wang C. Knijnenburg TA, et al. Cell Rep. 2018 Apr 3;23(1):239-254.e6. doi: 10.1016/j.celrep.2018.03.076. Cell Rep. 2018. PMID: 29617664 Free PMC article.
A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation.
Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, Chen J, Shmulevich I, Weissman JS, Curtis C, Califano A, Fu H, Crabtree GR, Kuo CJ. Lo YH, et al. Cancer Discov. 2021 Jun;11(6):1562-1581. doi: 10.1158/2159-8290.CD-20-1109. Epub 2021 Jan 15. Cancer Discov. 2021. PMID: 33451982 Free PMC article.
DNA-PK, ATM, and ATR: PIKKing on p53.
Ashley AK, Kemp CJ. Ashley AK, et al. Cell Cycle. 2018;17(3):275-276. doi: 10.1080/15384101.2017.1412147. Epub 2018 Apr 2. Cell Cycle. 2018. PMID: 29265907 Free PMC article. No abstract available.
CDK12: an emerging therapeutic target for cancer.
Lui GYL, Grandori C, Kemp CJ. Lui GYL, et al. J Clin Pathol. 2018 Nov;71(11):957-962. doi: 10.1136/jclinpath-2018-205356. Epub 2018 Aug 13. J Clin Pathol. 2018. PMID: 30104286 Free PMC article. Review.
Extraordinary clinical response to ibrutinib in low-grade ovarian cancer guided by organoid drug testing.
Gray HJ, Chatterjee P, Rosati R, Appleyard LR, Durenberger GJ, Diaz RL, Swan HA, Peretti D, Pollastro M, Ainge T, Kapeli K, Pereira S, Margossian AL, Banda K, Goff BA, Swisher EM, Bernard B, Kemp CJ, Grandori C. Gray HJ, et al. NPJ Precis Oncol. 2023 May 18;7(1):45. doi: 10.1038/s41698-023-00379-8. NPJ Precis Oncol. 2023. PMID: 37202426 Free PMC article.
Repurposing dasatinib for diffuse large B cell lymphoma.
Scuoppo C, Wang J, Persaud M, Mittan SK, Basso K, Pasqualucci L, Rabadan R, Inghirami G, Grandori C, Bosch F, Dalla-Favera R. Scuoppo C, et al. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16981-16986. doi: 10.1073/pnas.1905239116. Epub 2019 Aug 5. Proc Natl Acad Sci U S A. 2019. PMID: 31383760 Free PMC article.
Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma.
Moser R, Gurley KE, Nikolova O, Qin G, Joshi R, Mendez E, Shmulevich I, Ashley A, Grandori C, Kemp CJ. Moser R, et al. Oncogene. 2022 Jun;41(24):3355-3369. doi: 10.1038/s41388-022-02330-w. Epub 2022 May 10. Oncogene. 2022. PMID: 35538224
27 results