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Page 1
Targeting mutations in cancer.
Waarts MR, Stonestrom AJ, Park YC, Levine RL. Waarts MR, et al. J Clin Invest. 2022 Apr 15;132(8):e154943. doi: 10.1172/JCI154943. J Clin Invest. 2022. PMID: 35426374 Free PMC article. Review.
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.
Amor C, Fernández-Maestre I, Chowdhury S, Ho YJ, Nadella S, Graham C, Carrasco SE, Nnuji-John E, Feucht J, Hinterleitner C, Barthet VJA, Boyer JA, Mezzadra R, Wereski MG, Tuveson DA, Levine RL, Jones LW, Sadelain M, Lowe SW. Amor C, et al. Nat Aging. 2024 Mar;4(3):336-349. doi: 10.1038/s43587-023-00560-5. Epub 2024 Jan 24. Nat Aging. 2024. PMID: 38267706 Free PMC article.
Clonal hematopoiesis, aging and Alzheimer's disease.
Sánchez Vela P, Trowbridge JJ, Levine RL. Sánchez Vela P, et al. Nat Med. 2023 Jul;29(7):1605-1606. doi: 10.1038/s41591-023-02406-4. Nat Med. 2023. PMID: 37402877 No abstract available.
Challenges and opportunities for modeling aging and cancer.
Anczuków O, Airhart S, Chuang JH, Coussens LM, Kuchel GA, Korstanje R, Li S, Lucido AL, McAllister SS, Politi K, Polyak K, Ratliff T, Ren G, Trowbridge JJ, Ucar D, Palucka K. Anczuków O, et al. Cancer Cell. 2023 Apr 10;41(4):641-645. doi: 10.1016/j.ccell.2023.03.006. Epub 2023 Mar 30. Cancer Cell. 2023. PMID: 37001528 Free PMC article.
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells.
Waarts MR, Mowla S, Boileau M, Martinez Benitez AR, Sango J, Bagish M, Fernández-Maestre I, Shan Y, Eisman SE, Park YC, Wereski M, Csete I, O'Connor K, Romero-Vega AC, Miles LA, Xiao W, Wu X, Koche RP, Armstrong SA, Shih AH, Papapetrou EP, Butler JM, Cai SF, Bowman RL, Levine RL. Waarts MR, et al. Cancer Discov. 2024 Oct 4;14(10):1860-1878. doi: 10.1158/2159-8290.CD-23-1092. Cancer Discov. 2024. PMID: 38819218
16 results