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2016 4
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Page 1
Untangling Genetic Risk for Alzheimer's Disease.
Pimenova AA, Raj T, Goate AM. Pimenova AA, et al. Biol Psychiatry. 2018 Feb 15;83(4):300-310. doi: 10.1016/j.biopsych.2017.05.014. Epub 2017 May 22. Biol Psychiatry. 2018. PMID: 28666525 Free PMC article. Review.
Clonal hematopoiesis is associated with protection from Alzheimer's disease.
Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D, Yao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Beiser A, Bick AG, Bis JC, Fornage M, Longstreth WT Jr, Lopez OL, Natarajan P, Psaty BM, Satizabal CL, Weinstock J, Larson EB, Crane PK, Keene CD, Seshadri S, Satpathy AT, Montine TJ, Jaiswal S. Bouzid H, et al. Nat Med. 2023 Jul;29(7):1662-1670. doi: 10.1038/s41591-023-02397-2. Epub 2023 Jun 15. Nat Med. 2023. PMID: 37322115 Free PMC article.
Protective Variants in Alzheimer's Disease.
Andrews SJ, Fulton-Howard B, Goate A. Andrews SJ, et al. Curr Genet Med Rep. 2019 Mar;7(1):1-12. doi: 10.1007/s40142-019-0156-2. Epub 2019 Jan 24. Curr Genet Med Rep. 2019. PMID: 33117616 Free PMC article.
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, … See abstract for full author list ➔ Sims R, et al. Nat Genet. 2017 Sep;49(9):1373-1384. doi: 10.1038/ng.3916. Epub 2017 Jul 17. Nat Genet. 2017. PMID: 28714976 Free PMC article.
GWAS on family history of Alzheimer's disease.
Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, Hill WD, Davies G, Ritchie CW, Gale CR, Starr JM, Goate AM, Porteous DJ, Yang J, Evans KL, Deary IJ, Wray NR, Visscher PM. Marioni RE, et al. Transl Psychiatry. 2018 May 18;8(1):99. doi: 10.1038/s41398-018-0150-6. Transl Psychiatry. 2018. PMID: 29777097 Free PMC article.
Progranulin mutations in clinical and neuropathological Alzheimer's disease.
Vardarajan BN, Reyes-Dumeyer D, Piriz AL, Lantigua RA, Medrano M, Rivera D, Jiménez-Velázquez IZ, Martin E, Pericak-Vance MA, Bush W, Farrer L, Haines JL, Wang LS, Leung YY, Schellenberg G, Kukull W, De Jager P, Bennett DA, Schneider JA; Alzheimer's Disease Sequencing Project; Mayeux R. Vardarajan BN, et al. Alzheimers Dement. 2022 Dec;18(12):2458-2467. doi: 10.1002/alz.12567. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35258170 Free PMC article.
Estrogen activates Alzheimer's disease genes.
Ratnakumar A, Zimmerman SE, Jordan BA, Mar JC. Ratnakumar A, et al. Alzheimers Dement (N Y). 2019 Dec 9;5:906-917. doi: 10.1016/j.trci.2019.09.004. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31890855 Free PMC article.
60 results