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The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8+ T cells into innate-like effector cells with antitumor activity.
Oncoimmunology. 2013 Nov 1;2(11):e26442. doi: 10.4161/onci.26442. Epub 2013 Oct 9.
Oncoimmunology. 2013.
PMID: 24404427
Free PMC article.
Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor αSu/Fc fusion complex in syngeneic murine models of multiple myeloma.
Xu W, Jones M, Liu B, Zhu X, Johnson CB, Edwards AC, Kong L, Jeng EK, Han K, Marcus WD, Rubinstein MP, Rhode PR, Wong HC.
Xu W, et al.
Cancer Res. 2013 May 15;73(10):3075-86. doi: 10.1158/0008-5472.CAN-12-2357. Epub 2013 May 3.
Cancer Res. 2013.
PMID: 23644531
Free PMC article.
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