Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications

J Med Chem. 2012 Mar 8;55(5):1789-808. doi: 10.1021/jm201468j. Epub 2012 Jan 17.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Binding Sites
  • Drug Discovery
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Enzyme Inhibitors / therapeutic use
  • Epoxide Hydrolases / antagonists & inhibitors*
  • Epoxide Hydrolases / physiology
  • Humans
  • Models, Molecular
  • Solubility
  • Structure-Activity Relationship

Substances

  • Enzyme Inhibitors
  • Epoxide Hydrolases