R35 GM148239/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2022	2
2023	5
2024	2

1

Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal subunit regulation of the cardiac voltage-gated sodium channel.

Minard AY, Clark CJ, Ahern CA, Piper RC. Minard AY, et al. J Biol Chem. 2023 Sep;299(9):105132. doi: 10.1016/j.jbc.2023.105132. Epub 2023 Aug 6. J Biol Chem. 2023. PMID: 37544648 Free PMC article.

2

Chemically Acylated tRNAs are Functional in Zebrafish Embryos.

Brown W, Galpin JD, Rosenblum C, Tsang M, Ahern CA, Deiters A. Brown W, et al. J Am Chem Soc. 2023 Feb 1;145(4):2414-2420. doi: 10.1021/jacs.2c11452. Epub 2023 Jan 20. J Am Chem Soc. 2023. PMID: 36669466 Free PMC article.

3

Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel.

Strege PR, Cowan LM, Alcaino C, Mazzone A, Ahern CA, Milescu LS, Farrugia G, Beyder A. Strege PR, et al. Elife. 2023 Mar 13;12:e79271. doi: 10.7554/eLife.79271. Elife. 2023. PMID: 36912788 Free PMC article.

4

Role of a conserved ion-binding site tyrosine in ion selectivity of the Na+/K+ pump.

Spontarelli K, Infield DT, Nielsen HN, Holm R, Young VC, Galpin JD, Ahern CA, Vilsen B, Artigas P. Spontarelli K, et al. J Gen Physiol. 2022 Jul 4;154(7):e202113039. doi: 10.1085/jgp.202113039. Epub 2022 Jun 3. J Gen Physiol. 2022. PMID: 35657726 Free PMC article.

5

Real-time observation of functional specialization among phosphorylation sites in CFTR.

Infield DT, Schene ME, Fazan FS, Galles GD, Galpin JD, Ahern CA. Infield DT, et al. J Gen Physiol. 2023 Apr 3;155(4):e202213216. doi: 10.1085/jgp.202213216. Epub 2023 Jan 25. J Gen Physiol. 2023. PMID: 36695813 Free PMC article.

6

Backbone amides are determinants of Cl^- selectivity in CLC ion channels.

Leisle L, Lam K, Dehghani-Ghahnaviyeh S, Fortea E, Galpin JD, Ahern CA, Tajkhorshid E, Accardi A. Leisle L, et al. Nat Commun. 2022 Dec 6;13(1):7508. doi: 10.1038/s41467-022-35279-1. Nat Commun. 2022. PMID: 36473856 Free PMC article.

7

Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells.

Galles GD, Infield DT, Clark CJ, Hemshorn ML, Manikandan S, Fazan F, Rasouli A, Tajkhorshid E, Galpin JD, Cooley RB, Mehl RA, Ahern CA. Galles GD, et al. Nat Commun. 2023 Jan 4;14(1):59. doi: 10.1038/s41467-022-35761-w. Nat Commun. 2023. PMID: 36599844 Free PMC article.

8

Genetic Code Expansion for Mechanistic Studies in Ion Channels: An (Un)natural Union of Chemistry and Biology.

Infield DT, Schene ME, Galpin JD, Ahern CA. Infield DT, et al. Chem Rev. 2024 Oct 23;124(20):11523-11543. doi: 10.1021/acs.chemrev.4c00306. Epub 2024 Aug 29. Chem Rev. 2024. PMID: 39207057 Free PMC article. Review.

9

Conformational photo-trapping in Na_V1.5: Inferring local motions at the "inactivation gate".

Goodchild SJ, Ahern CA. Goodchild SJ, et al. Biophys J. 2024 Jul 16;123(14):2167-2175. doi: 10.1016/j.bpj.2024.04.017. Epub 2024 Apr 24. Biophys J. 2024. PMID: 38664963

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