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Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.
Science. 2015 May 15;348(6236):803-8. doi: 10.1126/science.aaa3828. Epub 2015 Apr 2.
Science. 2015.
PMID: 25837513
Free PMC article.
Clinical Trial.
pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens.
Hundal J, Carreno BM, Petti AA, Linette GP, Griffith OL, Mardis ER, Griffith M.
Hundal J, et al.
Genome Med. 2016 Jan 29;8(1):11. doi: 10.1186/s13073-016-0264-5.
Genome Med. 2016.
PMID: 26825632
Free PMC article.
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Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.
Linette GP, Becker-Hapak M, Skidmore ZL, Baroja ML, Xu C, Hundal J, Spencer DH, Fu W, Cummins C, Robnett M, Kaabinejadian S, Hildebrand WH, Magrini V, Demeter R, Krupnick AS, Griffith OL, Griffith M, Mardis ER, Carreno BM.
Linette GP, et al.
Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23662-23670. doi: 10.1073/pnas.1906026116. Epub 2019 Nov 4.
Proc Natl Acad Sci U S A. 2019.
PMID: 31685621
Free PMC article.
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