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A broad-spectrum antiviral targeting entry of enveloped viruses.
Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. doi: 10.1073/pnas.0909587107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133606 Free PMC article.
Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly.
Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Khachatoorian R, et al. Int J Antimicrob Agents. 2016 Apr;47(4):289-96. doi: 10.1016/j.ijantimicag.2016.01.012. Epub 2016 Mar 2. Int J Antimicrob Agents. 2016. PMID: 27013001 Free PMC article.