R21 AG071249/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2022	2
2023	6
2024	1

1

Endoplasmic reticulum stress and alterations of peroxiredoxins in aged hearts.

Chen Q, Thompson J, Hu Y, Lesnefsky EJ. Chen Q, et al. Mech Ageing Dev. 2023 Oct;215:111859. doi: 10.1016/j.mad.2023.111859. Epub 2023 Sep 1. Mech Ageing Dev. 2023. PMID: 37661065 Free PMC article.

2

Cardiomyocyte Pdk4 response is associated with metabolic maladaptation in aging.

Fatmi MK, Ren D, Fedorova J, Zoungrana LI, Wang H, Davitt K, Li Z, Iglesias M, Lesnefsky EJ, Krause-Hauch M, Li J. Fatmi MK, et al. Aging Cell. 2023 Apr;22(4):e13800. doi: 10.1111/acel.13800. Epub 2023 Feb 16. Aging Cell. 2023. PMID: 36797808 Free PMC article.

3

Time to Target Mitochondrial Reactive Oxygen Species Generation from Complex I.

Chen Q, Lesnefsky EJ. Chen Q, et al. Function (Oxf). 2022 Mar 23;3(2):zqac010. doi: 10.1093/function/zqac010. eCollection 2022. Function (Oxf). 2022. PMID: 35359911 Free PMC article. No abstract available.

4

Acute, High Dose Metformin Therapy at Reperfusion Decreases Infarct Size in the High-Risk Aging Heart.

Bates L, Krause-Hauch M, Wang H, Fatmi MK, Li Z, Chen Q, Ren D, Li J, Lesnefsky EJ. Bates L, et al. Aging Dis. 2023 Oct 1;14(5):1488-1491. doi: 10.14336/AD.2023.0205. Aging Dis. 2023. PMID: 37196121 Free PMC article.

5

Endoplasmic reticulum stress and mitochondrial dysfunction during aging: Role of sphingolipids.

Chen Q, Kovilakath A, Allegood J, Thompson J, Hu Y, Cowart LA, Lesnefsky EJ. Chen Q, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Oct;1868(10):159366. doi: 10.1016/j.bbalip.2023.159366. Epub 2023 Jul 18. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 37473835 Free PMC article.

6

Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3.

Iglesias M, Wang H, Krause-Hauch M, Ren D, Zoungrana LI, Li Z, Zhang J, Wei J, Yadav N, Patel K, Fatmi MK, Liu R, Lesnefsky EJ, Li J. Iglesias M, et al. Cells. 2023 Mar 8;12(6):845. doi: 10.3390/cells12060845. Cells. 2023. PMID: 36980186 Free PMC article.

7

Acute endoplasmic reticulum stress-induced mitochondria respiratory chain damage: The role of activated calpains.

Chen Q, Li L, Samidurai A, Thompson J, Hu Y, Willard B, Lesnefsky EJ. Chen Q, et al. FASEB J. 2024 Jan 31;38(2):e23404. doi: 10.1096/fj.202301158RR. FASEB J. 2024. PMID: 38197290

8

The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease.

Murphy J, Le TNV, Fedorova J, Yang Y, Krause-Hauch M, Davitt K, Zoungrana LI, Fatmi MK, Lesnefsky EJ, Li J, Ren D. Murphy J, et al. Front Cardiovasc Med. 2022 Feb 22;9:850538. doi: 10.3389/fcvm.2022.850538. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35274014 Free PMC article.

9

Administration of metformin rescues age-related vulnerability to ischemic insults through mitochondrial energy metabolism.

Li Z, Wang H, Zoungrana LI, James A, Slotabec L, Didik S, Fatmi MK, Krause-Hauch M, Lesnefsky EJ, Li J. Li Z, et al. Biochem Biophys Res Commun. 2023 Jun 4;659:46-53. doi: 10.1016/j.bbrc.2023.04.004. Epub 2023 Apr 5. Biochem Biophys Res Commun. 2023. PMID: 37031594 Free PMC article.

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