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Page 1
Allele-specific tumor spectrum in pten knockin mice.
Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, Rosol TJ, Eng C, Ostrowski MC, Leone G. Wang H, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5142-7. doi: 10.1073/pnas.0912524107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194734 Free PMC article.
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC. Mathsyaraja H, et al. Oncogene. 2015 Jul;34(28):3651-61. doi: 10.1038/onc.2014.294. Epub 2014 Sep 22. Oncogene. 2015. PMID: 25241894 Free PMC article.
E2f1-3 are critical for myeloid development.
Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G. Trikha P, et al. J Biol Chem. 2011 Feb 11;286(6):4783-95. doi: 10.1074/jbc.M110.182733. Epub 2010 Nov 28. J Biol Chem. 2011. PMID: 21115501 Free PMC article.
Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G, Ostrowski MC. Wallace JA, et al. PLoS One. 2013 Aug 16;8(8):e71533. doi: 10.1371/journal.pone.0071533. eCollection 2013. PLoS One. 2013. PMID: 23977064 Free PMC article.
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G. Trimboli AJ, et al. Nature. 2009 Oct 22;461(7267):1084-91. doi: 10.1038/nature08486. Nature. 2009. PMID: 19847259 Free PMC article.
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, Hallett M, Park M, Piper MG, Marsh CB, Yee LD, Jimenez RE, Nuovo G, Lawler SE, Chiocca EA, Leone G, Ostrowski MC. Bronisz A, et al. Nat Cell Biol. 2011 Dec 18;14(2):159-67. doi: 10.1038/ncb2396. Nat Cell Biol. 2011. PMID: 22179046 Free PMC article.