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A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function.
Mol Pharmacol. 2006 Nov;70(5):1630-42. doi: 10.1124/mol.106.026120. Epub 2006 Jul 31.
Mol Pharmacol. 2006.
PMID: 16880288
A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.
Sen N, Shi L, Beuming T, Weinstein H, Javitch JA.
Sen N, et al.
Neuropharmacology. 2005 Nov;49(6):780-90. doi: 10.1016/j.neuropharm.2005.08.014. Epub 2005 Oct 10.
Neuropharmacology. 2005.
PMID: 16216288
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