R01 NS117626/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	1
2022	4
2023	2
2024	1

1

C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation.

Manion J, Musser MA, Kuziel GA, Liu M, Shepherd A, Wang S, Lee PG, Zhao L, Zhang J, Marreddy RKR, Goldsmith JD, Yuan K, Hurdle JG, Gerhard R, Jin R, Rakoff-Nahoum S, Rao M, Dong M. Manion J, et al. Nature. 2023 Oct;622(7983):611-618. doi: 10.1038/s41586-023-06607-2. Epub 2023 Sep 12. Nature. 2023. PMID: 37699522 Free PMC article.

2

Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors.

Xiong X, Tian S, Yang P, Lebreton F, Bao H, Sheng K, Yin L, Chen P, Zhang J, Qi W, Ruan J, Wu H, Chen H, Breault DT, Wu H, Earl AM, Gilmore MS, Abraham J, Dong M. Xiong X, et al. Cell. 2022 Mar 31;185(7):1157-1171.e22. doi: 10.1016/j.cell.2022.02.002. Epub 2022 Mar 7. Cell. 2022. PMID: 35259335 Free PMC article.

3

CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor.

Xu Y, Viswanatha R, Sitsel O, Roderer D, Zhao H, Ashwood C, Voelcker C, Tian S, Raunser S, Perrimon N, Dong M. Xu Y, et al. Nature. 2022 Oct;610(7931):349-355. doi: 10.1038/s41586-022-05250-7. Epub 2022 Sep 28. Nature. 2022. PMID: 36171290 Free PMC article.

4

Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains.

Hodgins HP, Chen P, Lobb B, Wei X, Tremblay BJM, Mansfield MJ, Lee VCY, Lee PG, Coffin J, Duggan AT, Dolphin AE, Renaud G, Dong M, Doxey AC. Hodgins HP, et al. Nat Commun. 2023 Sep 6;14(1):5475. doi: 10.1038/s41467-023-41174-0. Nat Commun. 2023. PMID: 37673908 Free PMC article.

5

Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants.

Tian S, Xiong X, Zeng J, Wang S, Tremblay BJ, Chen P, Chen B, Liu M, Chen P, Sheng K, Zeve D, Qi W, Breault DT, Rodríguez C, Gerhard R, Jin R, Doxey AC, Dong M. Tian S, et al. Nat Commun. 2022 Nov 9;13(1):6786. doi: 10.1038/s41467-022-33964-9. Nat Commun. 2022. PMID: 36351897 Free PMC article.

6

Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms.

Tian S, Liu Y, Appleton E, Wang H, Church GM, Dong M. Tian S, et al. Cell Rep. 2022 Mar 8;38(10):110476. doi: 10.1016/j.celrep.2022.110476. Cell Rep. 2022. PMID: 35263584 Free PMC article.

7

Knockin mouse models demonstrate differential contributions of synaptotagmin-1 and -2 as receptors for botulinum neurotoxins.

Thaker H, Zhang J, Miyashita SI, Cristofaro V, Park S, Hashemi Gheinani A, Sullivan MP, Adam RM, Dong M. Thaker H, et al. PLoS Pathog. 2021 Oct 18;17(10):e1009994. doi: 10.1371/journal.ppat.1009994. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34662366 Free PMC article.

8

Activity of botulinum neurotoxin X and its structure when shielded by a non-toxic non-hemagglutinin protein.

Martínez-Carranza M, Škerlová J, Lee PG, Zhang J, Krč A, Sirohiwal A, Burgin D, Elliott M, Philippe J, Donald S, Hornby F, Henriksson L, Masuyer G, Kaila VRI, Beard M, Dong M, Stenmark P. Martínez-Carranza M, et al. Commun Chem. 2024 Aug 13;7(1):179. doi: 10.1038/s42004-024-01262-8. Commun Chem. 2024. PMID: 39138288 Free PMC article.

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