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2017 6
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Page 1
Blood-Brain Barrier: From Physiology to Disease and Back.
Sweeney MD, Zhao Z, Montagne A, Nelson AR, Zlokovic BV. Sweeney MD, et al. Physiol Rev. 2019 Jan 1;99(1):21-78. doi: 10.1152/physrev.00050.2017. Physiol Rev. 2019. PMID: 30280653 Free PMC article. Review.
The role of brain vasculature in neurodegenerative disorders.
Sweeney MD, Kisler K, Montagne A, Toga AW, Zlokovic BV. Sweeney MD, et al. Nat Neurosci. 2018 Oct;21(10):1318-1331. doi: 10.1038/s41593-018-0234-x. Epub 2018 Sep 24. Nat Neurosci. 2018. PMID: 30250261 Free PMC article. Review.
APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Reiman EM, Caselli RJ, Chui HC, Tcw J, Chen Y, Pa J, Conti PS, Law M, Toga AW, Zlokovic BV. Montagne A, et al. Nature. 2020 May;581(7806):71-76. doi: 10.1038/s41586-020-2247-3. Epub 2020 Apr 29. Nature. 2020. PMID: 32376954 Free PMC article.
Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.
Nation DA, Sweeney MD, Montagne A, Sagare AP, D'Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Chui HC, Law M, Toga AW, Zlokovic BV. Nation DA, et al. Nat Med. 2019 Feb;25(2):270-276. doi: 10.1038/s41591-018-0297-y. Epub 2019 Jan 14. Nat Med. 2019. PMID: 30643288 Free PMC article.
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.
Montagne A, Nikolakopoulou AM, Zhao Z, Sagare AP, Si G, Lazic D, Barnes SR, Daianu M, Ramanathan A, Go A, Lawson EJ, Wang Y, Mack WJ, Thompson PM, Schneider JA, Varkey J, Langen R, Mullins E, Jacobs RE, Zlokovic BV. Montagne A, et al. Nat Med. 2018 Mar;24(3):326-337. doi: 10.1038/nm.4482. Epub 2018 Feb 5. Nat Med. 2018. Retraction in: Nat Med. 2024 Apr;30(4):1215. doi: 10.1038/s41591-024-02935-6. PMID: 29400711 Free PMC article. Retracted.
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.
Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, Sagare AP, Lazic D, Sweeney MD, Kong P, Wang M, Owens NC, Lawson EJ, Xie X, Zhao Z, Zlokovic BV. Nikolakopoulou AM, et al. Nat Neurosci. 2019 Jul;22(7):1089-1098. doi: 10.1038/s41593-019-0434-z. Epub 2019 Jun 24. Nat Neurosci. 2019. PMID: 31235908 Free PMC article.
Vascular dysfunction-The disregarded partner of Alzheimer's disease.
Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Al-Shahi Salman R, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV. Sweeney MD, et al. Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222. Alzheimers Dement. 2019. PMID: 30642436 Free PMC article.
36 results