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Genomic frontiers in congenital heart disease.
Morton SU, Quiat D, Seidman JG, Seidman CE. Morton SU, et al. Nat Rev Cardiol. 2022 Jan;19(1):26-42. doi: 10.1038/s41569-021-00587-4. Epub 2021 Jul 16. Nat Rev Cardiol. 2022. PMID: 34272501 Free PMC article. Review.
Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency.
Ward T, Tai W, Morton S, Impens F, Van Damme P, Van Haver D, Timmerman E, Venturini G, Zhang K, Jang MY, Willcox JAL, Haghighi A, Gelb BD, Chung WK, Goldmuntz E, Porter GA Jr, Lifton RP, Brueckner M, Yost HJ, Bruneau BG, Gorham J, Kim Y, Pereira A, Homsy J, Benson CC, DePalma SR, Varland S, Chen CS, Arnesen T, Gevaert K, Seidman C, Seidman JG. Ward T, et al. Circ Res. 2021 Apr 16;128(8):1156-1169. doi: 10.1161/CIRCRESAHA.120.316966. Epub 2021 Feb 9. Circ Res. 2021. PMID: 33557580 Free PMC article. Clinical Trial.
Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes.
McKean DM, Zhang Q, Narayan P, Morton SU, Strohmenger V, Tang VT, McAllister S, Sharma A, Quiat D, Reichart D, DeLaughter DM, Wakimoto H, Gorham JM, Brown K, McDonough B, Willcox JA, Jang MY, DePalma SR, Ward T; Pediatric Cardiac Genomics Consortium Investigators; Kim R, Cleveland JD, Seidman JG, Seidman CE. McKean DM, et al. J Clin Invest. 2024 Jun 3;134(11):e167811. doi: 10.1172/JCI167811. J Clin Invest. 2024. PMID: 38828726 Free PMC article.