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Page 1
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.
Akbari P, Gilani A, Sosina O, Kosmicki JA, Khrimian L, Fang YY, Persaud T, Garcia V, Sun D, Li A, Mbatchou J, Locke AE, Benner C, Verweij N, Lin N, Hossain S, Agostinucci K, Pascale JV, Dirice E, Dunn M; Regeneron Genetics Center; DiscovEHR Collaboration; Kraus WE, Shah SH, Chen YI, Rotter JI, Rader DJ, Melander O, Still CD, Mirshahi T, Carey DJ, Berumen-Campos J, Kuri-Morales P, Alegre-Díaz J, Torres JM, Emberson JR, Collins R, Balasubramanian S, Hawes A, Jones M, Zambrowicz B, Murphy AJ, Paulding C, Coppola G, Overton JD, Reid JG, Shuldiner AR, Cantor M, Kang HM, Abecasis GR, Karalis K, Economides AN, Marchini J, Yancopoulos GD, Sleeman MW, Altarejos J, Della Gatta G, Tapia-Conyer R, Schwartzman ML, Baras A, Ferreira MAR, Lotta LA. Akbari P, et al. Science. 2021 Jul 2;373(6550):eabf8683. doi: 10.1126/science.abf8683. Science. 2021. PMID: 34210852 Free PMC article.
Gpr75-deficient mice are protected from high-fat diet-induced obesity.
Hossain S, Gilani A, Pascale J, Villegas E, Diegisser D, Agostinucci K, Kulaprathazhe MM, Dirice E, Garcia V, Schwartzman ML. Hossain S, et al. Obesity (Silver Spring). 2023 Apr;31(4):1024-1037. doi: 10.1002/oby.23692. Epub 2023 Feb 28. Obesity (Silver Spring). 2023. PMID: 36854900 Free PMC article.
The CYP/20-HETE/GPR75 axis in hypertension.
Froogh G, Garcia V, Laniado Schwartzman M. Froogh G, et al. Adv Pharmacol. 2022;94:1-25. doi: 10.1016/bs.apha.2022.02.003. Epub 2022 Mar 30. Adv Pharmacol. 2022. PMID: 35659370 Free PMC article. Review.
26 results