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Cardiac gene therapy with SERCA2a: from bench to bedside.
Gwathmey JK, Yerevanian AI, Hajjar RJ. Gwathmey JK, et al. J Mol Cell Cardiol. 2011 May;50(5):803-12. doi: 10.1016/j.yjmcc.2010.11.011. Epub 2010 Nov 18. J Mol Cell Cardiol. 2011. PMID: 21093451 Free PMC article. Review.
Refilling Intracellular Calcium Stores.
Kho C, Lee A, Jeong D, Hajjar RJ. Kho C, et al. Drug Discov Today Dis Mech. 2010 Summer;7(2):e145-e150. doi: 10.1016/j.ddmec.2010.08.004. Drug Discov Today Dis Mech. 2010. PMID: 21170146 Free PMC article.
Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy.
Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Peña JR, et al. J Mol Cell Cardiol. 2010 Dec;49(6):993-1002. doi: 10.1016/j.yjmcc.2010.09.010. Epub 2010 Sep 18. J Mol Cell Cardiol. 2010. PMID: 20854827 Free PMC article.
SUMO1-dependent modulation of SERCA2a in heart failure.
Kho C, Lee A, Jeong D, Oh JG, Chaanine AH, Kizana E, Park WJ, Hajjar RJ. Kho C, et al. Nature. 2011 Sep 7;477(7366):601-5. doi: 10.1038/nature10407. Nature. 2011. PMID: 21900893 Free PMC article.