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Page 1
Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N, Hargreaves VV, Zhu Q, Kurland JV, Hong J, Kim W, Sher F, Macias-Trevino C, Rogers JM, Kurita R, Nakamura Y, Yuan GC, Bauer DE, Xu J, Bulyk ML, Orkin SH. Liu N, et al. Cell. 2018 Apr 5;173(2):430-442.e17. doi: 10.1016/j.cell.2018.03.016. Epub 2018 Mar 29. Cell. 2018. PMID: 29606353 Free PMC article.
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE. Canver MC, et al. Nature. 2015 Nov 12;527(7577):192-7. doi: 10.1038/nature15521. Epub 2015 Sep 16. Nature. 2015. PMID: 26375006 Free PMC article.
Networking erythropoiesis.
Kerenyi MA, Orkin SH. Kerenyi MA, et al. J Exp Med. 2010 Nov 22;207(12):2537-41. doi: 10.1084/jem.20102260. J Exp Med. 2010. PMID: 21098097 Free PMC article. Review.
MOLECULAR MEDICINE: Found in Translation.
Orkin SH. Orkin SH. Med. 2021 Feb 12;2(2):122-136. doi: 10.1016/j.medj.2020.12.011. Epub 2021 Jan 12. Med. 2021. PMID: 33688634 Free PMC article. Review.
Evolution of nanobodies specific for BCL11A.
Yin M, Izadi M, Tenglin K, Viennet T, Zhai L, Zheng G, Arthanari H, Dassama LMK, Orkin SH. Yin M, et al. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218959120. doi: 10.1073/pnas.2218959120. Epub 2023 Jan 10. Proc Natl Acad Sci U S A. 2023. PMID: 36626555 Free PMC article.
Emerging Genetic Therapy for Sickle Cell Disease.
Orkin SH, Bauer DE. Orkin SH, et al. Annu Rev Med. 2019 Jan 27;70:257-271. doi: 10.1146/annurev-med-041817-125507. Epub 2018 Oct 24. Annu Rev Med. 2019. PMID: 30355263 Review.
60 results