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Prenatal exposure to PCBs in Cyp1a2 knock-out mice interferes with F1 fertility, impairs long-term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects.
Hufgard JR, Sprowles JLN, Pitzer EM, Koch SE, Jiang M, Wang Q, Zhang X, Biesiada J, Rubinstein J, Puga A, Williams MT, Vorhees CV. Hufgard JR, et al. J Appl Toxicol. 2019 Apr;39(4):603-621. doi: 10.1002/jat.3751. Epub 2018 Dec 18. J Appl Toxicol. 2019. PMID: 30561030
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