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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, Robertson NR, Rayner NW, Loh M, Kim BJ, Chiou J, Miguel-Escalada I, Della Briotta Parolo P, Lin K, Bragg F, Preuss MH, Takeuchi F, Nano J, Guo X, Lamri A, Nakatochi M, Scott RA, Lee JJ, Huerta-Chagoya A, Graff M, Chai JF, Parra EJ, Yao J, Bielak LF, Tabara Y, Hai Y, Steinthorsdottir V, Cook JP, Kals M, Grarup N, Schmidt EM, Pan I, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Long J, Sun M, Tong L, Chen WM, Ahmad M, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Lecoeur C, Prins BP, Nicolas A, Yanek LR, Chen G, Jensen RA, Tajuddin S, Kabagambe EK, An P, Xiang AH, Choi HS, Cade BE, Tan J, Flanagan J, Abaitua F, Adair LS, Adeyemo A, Aguilar-Salinas CA, Akiyama M, Anand SS, Bertoni A, Bian Z, Bork-Jensen J, Brandslund I, Brody JA, Brummett CM, Buchanan TA, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chuang LM, Cushman M, Das SK, de Silva HJ, Dedoussis G, Dimitrov L, Doumatey AP, Du S, Duan Q, Eckardt KU, Emery LS, Evans DS, Evans MK, Fischer K, Floyd JS, Ford I, Fornage M, F… See abstract for full author list ➔ Mahajan A, et al. Nat Genet. 2022 May;54(5):560-572. doi: 10.1038/s41588-022-01058-3. Epub 2022 May 12. Nat Genet. 2022. PMID: 35551307 Free PMC article.
Regulation of Tissue Inflammation by 12-Lipoxygenases.
Kulkarni A, Nadler JL, Mirmira RG, Casimiro I. Kulkarni A, et al. Biomolecules. 2021 May 11;11(5):717. doi: 10.3390/biom11050717. Biomolecules. 2021. PMID: 34064822 Free PMC article. Review.
Lipids and immunoinflammatory pathways of beta cell destruction.
Imai Y, Dobrian AD, Morris MA, Taylor-Fishwick DA, Nadler JL. Imai Y, et al. Diabetologia. 2016 Apr;59(4):673-8. doi: 10.1007/s00125-016-3890-y. Epub 2016 Feb 11. Diabetologia. 2016. PMID: 26868492 Free PMC article. Review.
Fatty acid-mediated signaling as a target for developing type 1 diabetes therapies.
Díaz Ludovico I, Sarkar S, Elliott E, Virtanen SM, Erlund I, Ramanadham S, Mirmira RG, Metz TO, Nakayasu ES. Díaz Ludovico I, et al. Expert Opin Ther Targets. 2023 Jul-Dec;27(9):793-806. doi: 10.1080/14728222.2023.2259099. Epub 2023 Sep 14. Expert Opin Ther Targets. 2023. PMID: 37706269 Free PMC article. Review.
57 results