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Page 1
Sirtuin chemical mechanisms.
Sauve AA. Sauve AA. Biochim Biophys Acta. 2010 Aug;1804(8):1591-603. doi: 10.1016/j.bbapap.2010.01.021. Epub 2010 Feb 2. Biochim Biophys Acta. 2010. PMID: 20132909 Free PMC article. Review.
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.
Bai P, Cantó C, Oudart H, Brunyánszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J. Bai P, et al. Cell Metab. 2011 Apr 6;13(4):461-468. doi: 10.1016/j.cmet.2011.03.004. Cell Metab. 2011. PMID: 21459330 Free PMC article.
Mechanism-based affinity capture of sirtuins.
Cen Y, Falco JN, Xu P, Youn DY, Sauve AA. Cen Y, et al. Org Biomol Chem. 2011 Feb 21;9(4):987-93. doi: 10.1039/c0ob00774a. Epub 2010 Dec 24. Org Biomol Chem. 2011. PMID: 21184005 Free PMC article.
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival.
Yang H, Yang T, Baur JA, Perez E, Matsui T, Carmona JJ, Lamming DW, Souza-Pinto NC, Bohr VA, Rosenzweig A, de Cabo R, Sauve AA, Sinclair DA. Yang H, et al. Cell. 2007 Sep 21;130(6):1095-107. doi: 10.1016/j.cell.2007.07.035. Cell. 2007. PMID: 17889652 Free PMC article.
Nicotinamide riboside kinase structures reveal new pathways to NAD+.
Tempel W, Rabeh WM, Bogan KL, Belenky P, Wojcik M, Seidle HF, Nedyalkova L, Yang T, Sauve AA, Park HW, Brenner C. Tempel W, et al. PLoS Biol. 2007 Oct 2;5(10):e263. doi: 10.1371/journal.pbio.0050263. PLoS Biol. 2007. PMID: 17914902 Free PMC article.
PARP-2 regulates SIRT1 expression and whole-body energy expenditure.
Bai P, Canto C, Brunyánszki A, Huber A, Szántó M, Cen Y, Yamamoto H, Houten SM, Kiss B, Oudart H, Gergely P, Menissier-de Murcia J, Schreiber V, Sauve AA, Auwerx J. Bai P, et al. Cell Metab. 2011 Apr 6;13(4):450-460. doi: 10.1016/j.cmet.2011.03.013. Cell Metab. 2011. PMID: 21459329 Free PMC article.
14 results