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Natural history of HFE simple heterozygosity for C282Y and H63D: a prospective 12-year study.
Zaloumis SG, Allen KJ, Bertalli NA, Turkovic L, Delatycki MB, Nicoll AJ, McLaren CE, English DR, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Gurrin LC; HealthIron Study Investigators. Zaloumis SG, et al. J Gastroenterol Hepatol. 2015 Apr;30(4):719-25. doi: 10.1111/jgh.12804. J Gastroenterol Hepatol. 2015. PMID: 25311314 Free PMC article.
HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidity.
Gurrin LC, Bertalli NA, Dalton GW, Osborne NJ, Constantine CC, McLaren CE, English DR, Gertig DM, Delatycki MB, Nicoll AJ, Southey MC, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Allen KJ; HealthIron Study Investigators. Gurrin LC, et al. Hepatology. 2009 Jul;50(1):94-101. doi: 10.1002/hep.22972. Hepatology. 2009. PMID: 19554541 Free PMC article.
HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.
Osborne NJ, Gurrin LC, Allen KJ, Constantine CC, Delatycki MB, McLaren CE, Gertig DM, Anderson GJ, Southey MC, Olynyk JK, Powell LW, Hopper JL, Giles GG, English DR. Osborne NJ, et al. Hepatology. 2010 Apr;51(4):1311-8. doi: 10.1002/hep.23448. Hepatology. 2010. PMID: 20099304 Free PMC article.
HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.
Warne CD, Zaloumis SG, Bertalli NA, Delatycki MB, Nicoll AJ, McLaren CE, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Allen KJ, Gurrin LC; HealthIron Study Investigators. Warne CD, et al. J Gastroenterol Hepatol. 2017 Apr;32(4):797-802. doi: 10.1111/jgh.13621. J Gastroenterol Hepatol. 2017. PMID: 27784128 Free PMC article.
A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis.
Constantine CC, Anderson GJ, Vulpe CD, McLaren CE, Bahlo M, Yeap HL, Gertig DM, Osborne NJ, Bertalli NA, Beckman KB, Chen V, Matak P, McKie AT, Delatycki MB, Olynyk JK, English DR, Southey MC, Giles GG, Hopper JL, Allen KJ, Gurrin LC. Constantine CC, et al. Br J Haematol. 2009 Oct;147(1):140-9. doi: 10.1111/j.1365-2141.2009.07843.x. Epub 2009 Aug 10. Br J Haematol. 2009. PMID: 19673882 Free PMC article.