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Stem cell modeling of nervous system tumors.
Furnari FB, Anastasaki C, Bian S, Fine HA, Koga T, Le LQ, Rodriguez FJ, Gutmann DH. Furnari FB, et al. Dis Model Mech. 2024 Feb 1;17(2):dmm050533. doi: 10.1242/dmm.050533. Epub 2024 Feb 14. Dis Model Mech. 2024. PMID: 38353122 Free PMC article. Review.
EGFR, the Lazarus target for precision oncology in glioblastoma.
Lin B, Ziebro J, Smithberger E, Skinner KR, Zhao E, Cloughesy TF, Binder ZA, O'Rourke DM, Nathanson DA, Furnari FB, Miller CR. Lin B, et al. Neuro Oncol. 2022 Dec 1;24(12):2035-2062. doi: 10.1093/neuonc/noac204. Neuro Oncol. 2022. PMID: 36125064 Free PMC article. Review.
Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy.
Contadini C, Ferri A, Di Martile M, Cirotti C, Del Bufalo D, De Nicola F, Pallocca M, Fanciulli M, Sacco F, Donninelli G, Capone A, Volpe E, Keller N, Miki S, Kawauchi D, Stupack D, Furnari F, Barilà D. Contadini C, et al. Cell Death Differ. 2023 Feb;30(2):417-428. doi: 10.1038/s41418-022-01093-x. Epub 2022 Dec 2. Cell Death Differ. 2023. PMID: 36460775 Free PMC article.
Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas.
Bredel M, Espinosa L, Kim H, Scholtens DM, McElroy JP, Rajbhandari R, Meng W, Kollmeyer TM, Malta TM, Quezada MA, Harsh GR, Lobo-Jarne T, Solé L, Merati A, Nagaraja S, Nair S, White JJ, Thudi NK, Fleming JL, Webb A, Natsume A, Ogawa S, Weber RG, Bertran J, Haque SJ, Hentschel B, Miller CR, Furnari FB, Chan TA, Grosu AL, Weller M, Barnholtz-Sloan JS, Monje M, Noushmehr H, Jenkins RB, Rogers CL, MacDonald DR, Pugh SL, Chakravarti A. Bredel M, et al. Cell Rep Med. 2023 Jun 20;4(6):101082. doi: 10.1016/j.xcrm.2023.101082. Cell Rep Med. 2023. PMID: 37343523 Free PMC article.
Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars.
Skinner KR, Koga T, Miki S, Gruener RF, Grigore FN, Torii EH, Seelig DM, Suzuki Y, Kawauchi D, Lin B, Malicki DM, Chen CC, Benveniste EN, Patel RP, McFarland BC, Huang RS, Jones C, Mackay A, Miller CR, Furnari FB. Skinner KR, et al. bioRxiv [Preprint]. 2023 Feb 24:2023.02.24.528982. doi: 10.1101/2023.02.24.528982. bioRxiv. 2023. PMID: 36865329 Free PMC article. Preprint.
13 results