R01 CA251928/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	4
2022	3
2023	4
2024	2

1

Liver homeostasis is maintained by midlobular zone 2 hepatocytes.

Wei Y, Wang YG, Jia Y, Li L, Yoon J, Zhang S, Wang Z, Zhang Y, Zhu M, Sharma T, Lin YH, Hsieh MH, Albrecht JH, Le PT, Rosen CJ, Wang T, Zhu H. Wei Y, et al. Science. 2021 Feb 26;371(6532):eabb1625. doi: 10.1126/science.abb1625. Science. 2021. PMID: 33632817 Free PMC article.

2

In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration.

Jia Y, Li L, Lin YH, Gopal P, Shen S, Zhou K, Yu X, Sharma T, Zhang Y, Siegwart DJ, Ready JM, Zhu H. Jia Y, et al. Cell Stem Cell. 2022 Mar 3;29(3):372-385.e8. doi: 10.1016/j.stem.2022.01.001. Epub 2022 Jan 31. Cell Stem Cell. 2022. PMID: 35090595 Free PMC article.

3

Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.

Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. Wang Z, et al. Cell. 2023 Apr 27;186(9):1968-1984.e20. doi: 10.1016/j.cell.2023.03.014. Epub 2023 Apr 10. Cell. 2023. PMID: 37040760 Free PMC article.

4

IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration.

Lin YH, Wei Y, Zeng Q, Wang Y, Pagani CA, Li L, Zhu M, Wang Z, Hsieh MH, Corbitt N, Zhang Y, Sharma T, Wang T, Zhu H. Lin YH, et al. Cell Stem Cell. 2023 May 4;30(5):665-676.e4. doi: 10.1016/j.stem.2023.04.007. Cell Stem Cell. 2023. PMID: 37146585 Free PMC article.

5

Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy.

Zhang D, Wang G, Yu X, Wei T, Farbiak L, Johnson LT, Taylor AM, Xu J, Hong Y, Zhu H, Siegwart DJ. Zhang D, et al. Nat Nanotechnol. 2022 Jul;17(7):777-787. doi: 10.1038/s41565-022-01122-3. Epub 2022 May 12. Nat Nanotechnol. 2022. PMID: 35551240 Free PMC article.

6

In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration.

Lin YH, Zeng Q, Jia Y, Wang Z, Li L, Hsieh MH, Cheng Q, Pagani CA, Livingston N, Lee J, Zhang Y, Sharma T, Siegwart DJ, Yimlamai D, Levi B, Zhu H. Lin YH, et al. Hepatology. 2023 Oct 1;78(4):1133-1148. doi: 10.1097/HEP.0000000000000402. Epub 2023 Apr 12. Hepatology. 2023. PMID: 37039560 Free PMC article.

7

A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence.

Cheng Y, Wang S, Zhang H, Lee JS, Ni C, Guo J, Chen E, Wang S, Acharya A, Chang TC, Buszczak M, Zhu H, Mendell JT. Cheng Y, et al. Cell. 2024 Aug 22;187(17):4770-4789.e23. doi: 10.1016/j.cell.2024.06.019. Epub 2024 Jul 8. Cell. 2024. PMID: 38981482 Free article.

8

Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis.

Venkateswaran N, Garcia R, Lafita-Navarro MC, Hao YH, Perez-Castro L, Nogueira PAS, Solmonson A, Mender I, Kilgore JA, Fang S, Brown IN, Li L, Parks E, Lopes Dos Santos I, Bhaskar M, Kim J, Jia Y, Lemoff A, Grishin NV, Kinch L, Xu L, Williams NS, Shay JW, DeBerardinis RJ, Zhu H, Conacci-Sorrell M. Venkateswaran N, et al. Nat Commun. 2024 May 20;15(1):4266. doi: 10.1038/s41467-024-47868-3. Nat Commun. 2024. PMID: 38769298 Free PMC article.

9

Genetic and Cellular Contributions to Liver Regeneration.

Liang R, Lin YH, Zhu H. Liang R, et al. Cold Spring Harb Perspect Biol. 2021 Nov 8;14(9):a040832. doi: 10.1101/cshperspect.a040832. Online ahead of print. Cold Spring Harb Perspect Biol. 2021. PMID: 34750173 Free PMC article.

10

Overcoming Expressional Drop-outs in Lineage Reconstruction from Single-Cell RNA-Sequencing Data.

Lu T, Park S, Zhu J, Wang Y, Zhan X, Wang X, Wang L, Zhu H, Wang T. Lu T, et al. Cell Rep. 2021 Jan 5;34(1):108589. doi: 10.1016/j.celrep.2020.108589. Cell Rep. 2021. PMID: 33406427 Free article.

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