R01 CA221158/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	2
2018	3
2019	1
2020	1
2021	4
2022	3
2023	1
2024	2

1

Neutrophils: Musketeers against immunotherapy.

Zahid KR, Raza U, Tumbath S, Jiang L, Xu W, Huang X. Zahid KR, et al. Front Oncol. 2022 Aug 25;12:975981. doi: 10.3389/fonc.2022.975981. eCollection 2022. Front Oncol. 2022. PMID: 36091114 Free PMC article. Review.

2

Modulators of Redox Metabolism in Head and Neck Cancer.

Chen X, Mims J, Huang X, Singh N, Motea E, Planchon SM, Beg M, Tsang AW, Porosnicu M, Kemp ML, Boothman DA, Furdui CM. Chen X, et al. Antioxid Redox Signal. 2018 Dec 1;29(16):1660-1690. doi: 10.1089/ars.2017.7423. Epub 2017 Dec 20. Antioxid Redox Signal. 2018. PMID: 29113454 Free PMC article. Review.

3

Detecting Attomolar DNA-Damaging Anticancer Drug Activity in Cell Lysates with Electrochemical DNA Devices.

Wettasinghe AP, Singh N, Starcher CL, DiTusa CC, Ishak-Boushaki Z, Kahanda D, McMullen R, Motea EA, Slinker JD. Wettasinghe AP, et al. ACS Sens. 2021 Jul 23;6(7):2622-2629. doi: 10.1021/acssensors.1c00365. Epub 2021 Jun 22. ACS Sens. 2021. PMID: 34156840 Free PMC article.

4

NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance.

Li X, Liu Z, Zhang A, Han C, Shen A, Jiang L, Boothman DA, Qiao J, Wang Y, Huang X, Fu YX. Li X, et al. Nat Commun. 2019 Jul 19;10(1):3251. doi: 10.1038/s41467-019-11238-1. Nat Commun. 2019. PMID: 31324798 Free PMC article.

5

Following anticancer drug activity in cell lysates with DNA devices.

Kahanda D, Singh N, Boothman DA, Slinker JD. Kahanda D, et al. Biosens Bioelectron. 2018 Nov 15;119:1-9. doi: 10.1016/j.bios.2018.07.059. Epub 2018 Jul 30. Biosens Bioelectron. 2018. PMID: 30098460 Free PMC article.

6

PCNA inhibition enhances the cytotoxicity of β-lapachone in NQO1-Positive cancer cells by augmentation of oxidative stress-induced DNA damage.

Su X, Wang J, Jiang L, Chen Y, Lu T, Mendonca MS, Huang X. Su X, et al. Cancer Lett. 2021 Oct 28;519:304-314. doi: 10.1016/j.canlet.2021.07.040. Epub 2021 Jul 27. Cancer Lett. 2021. PMID: 34329742 Free PMC article.

7

KP372-1-Induced AKT Hyperactivation Blocks DNA Repair to Synergize With PARP Inhibitor Rucaparib via Inhibiting FOXO3a/GADD45α Pathway.

Jiang L, Liu Y, Su X, Wang J, Zhao Y, Tumbath S, Kilgore JA, Williams NS, Chen Y, Wang X, Mendonca MS, Lu T, Fu YX, Huang X. Jiang L, et al. Front Oncol. 2022 Sep 20;12:976292. doi: 10.3389/fonc.2022.976292. eCollection 2022. Front Oncol. 2022. PMID: 36203459 Free PMC article.

8

β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation.

Zhao W, Jiang L, Fang T, Fang F, Liu Y, Zhao Y, You Y, Zhou H, Su X, Wang J, Liu S, Chen Y, Wan J, Huang X. Zhao W, et al. Front Oncol. 2021 Oct 5;11:747282. doi: 10.3389/fonc.2021.747282. eCollection 2021. Front Oncol. 2021. PMID: 34676172 Free PMC article.

9

Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill NQO1-Positive Pancreatic Cancer Cells.

Jiang L, Liu Y, Tumbath S, Boudreau MW, Chatkewitz LE, Wang J, Su X, Zahid KR, Li K, Chen Y, Yang K, Hergenrother PJ, Huang X. Jiang L, et al. Antioxid Redox Signal. 2024 Jul;41(1-3):74-92. doi: 10.1089/ars.2022.0224. Epub 2024 Jan 8. Antioxid Redox Signal. 2024. PMID: 37950707

10

Synergistic Effect of β-Lapachone and Aminooxyacetic Acid on Central Metabolism in Breast Cancer.

Chang MC, Mahar R, McLeod MA, Giacalone AG, Huang X, Boothman DA, Merritt ME. Chang MC, et al. Nutrients. 2022 Jul 22;14(15):3020. doi: 10.3390/nu14153020. Nutrients. 2022. PMID: 35893874 Free PMC article.

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