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Page 1
Temozolomide Sensitizes MGMT-Deficient Tumor Cells to ATR Inhibitors.
Jackson CB, Noorbakhsh SI, Sundaram RK, Kalathil AN, Ganesa S, Jia L, Breslin H, Burgenske DM, Gilad O, Sarkaria JN, Bindra RS. Jackson CB, et al. Cancer Res. 2019 Sep 1;79(17):4331-4338. doi: 10.1158/0008-5472.CAN-18-3394. Epub 2019 Jul 4. Cancer Res. 2019. PMID: 31273061 Free PMC article.
Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity.
Gayle S, Aiello R, Leelatian N, Beckta JM, Bechtold J, Bourassa P, Csengery J, Maguire RJ, Marshall D, Sundaram RK, Van Doorn J, Jones K, Moore H, Lopresti-Morrow L, Paradis T, Tylaska L, Zhang Q, Visca H, Reshetnyak YK, Andreev OA, Engelman DM, Glazer PM, Bindra RS, Paralkar VM. Gayle S, et al. NAR Cancer. 2021 Jun 4;3(2):zcab021. doi: 10.1093/narcan/zcab021. eCollection 2021 Jun. NAR Cancer. 2021. PMID: 34316708 Free PMC article.
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
Sulkowski PL, Oeck S, Dow J, Economos NG, Mirfakhraie L, Liu Y, Noronha K, Bao X, Li J, Shuch BM, King MC, Bindra RS, Glazer PM. Sulkowski PL, et al. Nature. 2020 Jun;582(7813):586-591. doi: 10.1038/s41586-020-2363-0. Epub 2020 Jun 3. Nature. 2020. PMID: 32494005 Free PMC article.
Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma.
Khang M, Lee JH, Lee T, Suh HW, Lee S, Cavaliere A, Rushing A, Geraldo LH, Belitzky E, Rossano S, de Feyter HM, Shin K, Huttner A, Roussel MF, Thomas JL, Carson RE, Marquez-Nostra B, Bindra RS, Saltzman WM. Khang M, et al. Sci Transl Med. 2023 Nov;15(720):eadi1617. doi: 10.1126/scitranslmed.adi1617. Epub 2023 Nov 1. Sci Transl Med. 2023. PMID: 37910601 Free PMC article.
Correction to 'Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity'.
Gayle S, Aiello R, Leelatian N, Beckta JM, Bechtold J, Bourassa P, Csengery J, Maguire RJ, Marshall D, Sundaram RK, Van Doorn J, Jones K, Moore H, Lopresti-Morrow L, Paradis T, Tylaska L, Zhang Q, Visca H, Reshetnyak YK, Andreev OA, Engelman DM, Glazer PM, Bindra RS, Paralkar VM. Gayle S, et al. NAR Cancer. 2021 Dec 7;3(4):zcab047. doi: 10.1093/narcan/zcab047. eCollection 2021 Dec. NAR Cancer. 2021. PMID: 34888524 Free PMC article.
Gray Areas in the Gray Matter: IDH1/2 Mutations in Glioma.
van den Bent MJ, Mellinghoff IK, Bindra RS. van den Bent MJ, et al. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-8. doi: 10.1200/EDBK_280967. Am Soc Clin Oncol Educ Book. 2020. PMID: 32186930 Free PMC article. Review.
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