R01 CA136512/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	1
2012	1
2014	2
2015	1
2016	1
2019	1
2020	1
2021	2
2024	0

1

BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.

Vohhodina J, Goehring LJ, Liu B, Kong Q, Botchkarev VV Jr, Huynh M, Liu Z, Abderazzaq FO, Clark AP, Ficarro SB, Marto JA, Hatchi E, Livingston DM. Vohhodina J, et al. Nat Commun. 2021 Jun 10;12(1):3542. doi: 10.1038/s41467-021-23716-6. Nat Commun. 2021. PMID: 34112789 Free PMC article.

2

Mechanisms of BRCA1 tumor suppression.

Silver DP, Livingston DM. Silver DP, et al. Cancer Discov. 2012 Aug;2(8):679-84. doi: 10.1158/2159-8290.CD-12-0221. Epub 2012 Jul 27. Cancer Discov. 2012. PMID: 22843421 Free PMC article. Review.

3

BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2-RAD52.

Hatchi E, Goehring L, Landini S, Skourti-Stathaki K, DeConti DK, Abderazzaq FO, Banerjee P, Demers TM, Wang YE, Quackenbush J, Livingston DM. Hatchi E, et al. Nature. 2021 Mar;591(7851):665-670. doi: 10.1038/s41586-020-03150-2. Epub 2021 Feb 3. Nature. 2021. PMID: 33536619 Free PMC article.

4

Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.

Wang H, Xiang D, Liu B, He A, Randle HJ, Zhang KX, Dongre A, Sachs N, Clark AP, Tao L, Chen Q, Botchkarev VV Jr, Xie Y, Dai N, Clevers H, Li Z, Livingston DM. Wang H, et al. Cell. 2019 Jun 27;178(1):135-151.e19. doi: 10.1016/j.cell.2019.06.002. Cell. 2019. PMID: 31251913 Free PMC article.

5

BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.

Wang H, Bierie B, Li AG, Pathania S, Toomire K, Dimitrov SD, Liu B, Gelman R, Giobbie-Hurder A, Feunteun J, Polyak K, Livingston DM. Wang H, et al. Mol Cell. 2016 Jul 21;63(2):277-292. doi: 10.1016/j.molcel.2016.05.038. Epub 2016 Jun 30. Mol Cell. 2016. PMID: 27373334 Free PMC article.

6

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, Beroukhim R, Marto JA, Vidal M, Gaudet S, Hill DE, Livingston DM. Hill SJ, et al. Genes Dev. 2014 Sep 1;28(17):1957-75. doi: 10.1101/gad.241620.114. Genes Dev. 2014. PMID: 25184681 Free PMC article.

7

RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci.

Vohhodina J, Toomire KJ, Petit SA, Micevic G, Kumari G, Botchkarev VV Jr, Li Z, Livingston DM, Hu Y. Vohhodina J, et al. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2084-2091. doi: 10.1073/pnas.1908003117. Epub 2020 Jan 13. Proc Natl Acad Sci U S A. 2020. PMID: 31932421 Free PMC article.

8

BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.

Hatchi E, Skourti-Stathaki K, Ventz S, Pinello L, Yen A, Kamieniarz-Gdula K, Dimitrov S, Pathania S, McKinney KM, Eaton ML, Kellis M, Hill SJ, Parmigiani G, Proudfoot NJ, Livingston DM. Hatchi E, et al. Mol Cell. 2015 Feb 19;57(4):636-647. doi: 10.1016/j.molcel.2015.01.011. Mol Cell. 2015. PMID: 25699710 Free PMC article.

9

BRCA1 pathway function in basal-like breast cancer cells.

Hill SJ, Clark AP, Silver DP, Livingston DM. Hill SJ, et al. Mol Cell Biol. 2014 Oct;34(20):3828-42. doi: 10.1128/MCB.01646-13. Epub 2014 Aug 4. Mol Cell Biol. 2014. PMID: 25092866 Free PMC article.

10

RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci.

Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston DM. Hu Y, et al. Genes Dev. 2011 Apr 1;25(7):685-700. doi: 10.1101/gad.2011011. Epub 2011 Mar 15. Genes Dev. 2011. PMID: 21406551 Free PMC article.

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