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61 results

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Page 1
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Dentro SC, Leshchiner I, Haase K, Tarabichi M, Wintersinger J, Deshwar AG, Yu K, Rubanova Y, Macintyre G, Demeulemeester J, Vázquez-García I, Kleinheinz K, Livitz DG, Malikic S, Donmez N, Sengupta S, Anur P, Jolly C, Cmero M, Rosebrock D, Schumacher SE, Fan Y, Fittall M, Drews RM, Yao X, Watkins TBK, Lee J, Schlesner M, Zhu H, Adams DJ, McGranahan N, Swanton C, Getz G, Boutros PC, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Martincorena I, Markowetz F, Mustonen V, Yuan K, Gerstung M, Spellman PT, Wang W, Morris QD, Wedge DC, Van Loo P; PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium. Dentro SC, et al. Cell. 2021 Apr 15;184(8):2239-2254.e39. doi: 10.1016/j.cell.2021.03.009. Epub 2021 Apr 7. Cell. 2021. PMID: 33831375 Free PMC article.
The evolutionary history of 2,658 cancers.
Gerstung M, Jolly C, Leshchiner I, Dentro SC, Gonzalez S, Rosebrock D, Mitchell TJ, Rubanova Y, Anur P, Yu K, Tarabichi M, Deshwar A, Wintersinger J, Kleinheinz K, Vázquez-García I, Haase K, Jerman L, Sengupta S, Macintyre G, Malikic S, Donmez N, Livitz DG, Cmero M, Demeulemeester J, Schumacher S, Fan Y, Yao X, Lee J, Schlesner M, Boutros PC, Bowtell DD, Zhu H, Getz G, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Markowetz F, Mustonen V, Yuan K, Wang W, Morris QD; PCAWG Evolution & Heterogeneity Working Group; Spellman PT, Wedge DC, Van Loo P; PCAWG Consortium. Gerstung M, et al. Nature. 2020 Feb;578(7793):122-128. doi: 10.1038/s41586-019-1907-7. Epub 2020 Feb 6. Nature. 2020. PMID: 32025013 Free PMC article.
Innovative trial design in precision oncology.
Tsimberidou AM, Müller P, Ji Y. Tsimberidou AM, et al. Semin Cancer Biol. 2022 Sep;84:284-292. doi: 10.1016/j.semcancer.2020.09.006. Epub 2020 Oct 3. Semin Cancer Biol. 2022. PMID: 33022355 Review.
Scalable Bayesian Nonparametric Clustering and Classification.
Ni Y, Müller P, Diesendruck M, Williamson S, Zhu Y, Ji Y. Ni Y, et al. J Comput Graph Stat. 2020;29(1):53-65. doi: 10.1080/10618600.2019.1624366. Epub 2019 Jul 19. J Comput Graph Stat. 2020. PMID: 32982129 Free PMC article.
A nonparametric Bayesian basket trial design.
Xu Y, Müller P, Tsimberidou AM, Berry D. Xu Y, et al. Biom J. 2019 Sep;61(5):1160-1174. doi: 10.1002/bimj.201700162. Epub 2018 May 28. Biom J. 2019. PMID: 29808479 Free PMC article.
Clinical Trial Design as a Decision Problem.
Müller P, Xu Y, Thall PF. Müller P, et al. Appl Stoch Models Bus Ind. 2017 May-Jun;33(3):296-301. doi: 10.1002/asmb.2222. Epub 2017 Jan 13. Appl Stoch Models Bus Ind. 2017. PMID: 29200977 Free PMC article.
Imaging-Genomic Study of Head and Neck Squamous Cell Carcinoma: Associations Between Radiomic Phenotypes and Genomic Mechanisms via Integration of The Cancer Genome Atlas and The Cancer Imaging Archive.
Zhu Y, Mohamed ASR, Lai SY, Yang S, Kanwar A, Wei L, Kamal M, Sengupta S, Elhalawani H, Skinner H, Mackin DS, Shiao J, Messer J, Wong A, Ding Y, Zhang L, Court L, Ji Y, Fuller CD. Zhu Y, et al. JCO Clin Cancer Inform. 2019 Feb;3:1-9. doi: 10.1200/CCI.18.00073. JCO Clin Cancer Inform. 2019. PMID: 30730765 Free PMC article.
61 results