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HER-2-directed, small-molecule antagonists.
Arkin M, Moasser MM. Arkin M, et al. Curr Opin Investig Drugs. 2008 Dec;9(12):1264-76. Curr Opin Investig Drugs. 2008. PMID: 19037833 Free PMC article. Review.
Resiliency and vulnerability in the HER2-HER3 tumorigenic driver.
Amin DN, Sergina N, Ahuja D, McMahon M, Blair JA, Wang D, Hann B, Koch KM, Shokat KM, Moasser MM. Amin DN, et al. Sci Transl Med. 2010 Jan 27;2(16):16ra7. doi: 10.1126/scitranslmed.3000389. Sci Transl Med. 2010. PMID: 20371474 Free PMC article.
A phase I study of a 2-day lapatinib chemosensitization pulse preceding nanoparticle albumin-bound Paclitaxel for advanced solid malignancies.
Chien AJ, Illi JA, Ko AH, Korn WM, Fong L, Chen LM, Kashani-Sabet M, Ryan CJ, Rosenberg JE, Dubey S, Small EJ, Jahan TM, Hylton NM, Yeh BM, Huang Y, Koch KM, Moasser MM. Chien AJ, et al. Clin Cancer Res. 2009 Sep 1;15(17):5569-75. doi: 10.1158/1078-0432.CCR-09-0522. Epub 2009 Aug 25. Clin Cancer Res. 2009. PMID: 19706807 Free PMC article. Clinical Trial.