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ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain.
Yiin JJ, Hu B, Schornack PA, Sengar RS, Liu KW, Feng H, Lieberman FS, Chiou SH, Sarkaria JN, Wiener EC, Ma HI, Cheng SY. Yiin JJ, et al. Mol Cancer Ther. 2010 Apr;9(4):929-41. doi: 10.1158/1535-7163.MCT-09-0953. Epub 2010 Apr 6. Mol Cancer Ther. 2010. PMID: 20371720 Free PMC article.