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SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.
Cell Death Differ. 2011 Dec;18(12):1904-13. doi: 10.1038/cdd.2011.71. Epub 2011 Jun 3.
Cell Death Differ. 2011.
PMID: 21637290
Free PMC article.
p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis.
Talos F, Abraham A, Vaseva AV, Holembowski L, Tsirka SE, Scheel A, Bode D, Dobbelstein M, Brück W, Moll UM.
Talos F, et al.
Cell Death Differ. 2010 Dec;17(12):1816-29. doi: 10.1038/cdd.2010.131.
Cell Death Differ. 2010.
PMID: 21076477
Free PMC article.
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