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Page 1
Atypical E2F repressors and activators coordinate placental development.
Ouseph MM, Li J, Chen HZ, Pécot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G. Ouseph MM, et al. Dev Cell. 2012 Apr 17;22(4):849-62. doi: 10.1016/j.devcel.2012.01.013. Dev Cell. 2012. PMID: 22516201 Free PMC article.
Canonical and atypical E2Fs regulate the mammalian endocycle.
Chen HZ, Ouseph MM, Li J, Pécot T, Chokshi V, Kent L, Bae S, Byrne M, Duran C, Comstock G, Trikha P, Mair M, Senapati S, Martin CK, Gandhi S, Wilson N, Liu B, Huang YW, Thompson JC, Raman S, Singh S, Leone M, Machiraju R, Huang K, Mo X, Fernandez S, Kalaszczynska I, Wolgemuth DJ, Sicinski P, Huang T, Jin V, Leone G. Chen HZ, et al. Nat Cell Biol. 2012 Nov;14(11):1192-202. doi: 10.1038/ncb2595. Epub 2012 Oct 14. Nat Cell Biol. 2012. PMID: 23064266 Free PMC article.
E2f1-3 are critical for myeloid development.
Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G. Trikha P, et al. J Biol Chem. 2011 Feb 11;286(6):4783-95. doi: 10.1074/jbc.M110.182733. Epub 2010 Nov 28. J Biol Chem. 2011. PMID: 21115501 Free PMC article.
Cell proliferation in the absence of E2F1-3.
Wenzel PL, Chong JL, Sáenz-Robles MT, Ferrey A, Hagan JP, Gomez YM, Rajmohan R, Sharma N, Chen HZ, Pipas JM, Robinson ML, Leone G. Wenzel PL, et al. Dev Biol. 2011 Mar 1;351(1):35-45. doi: 10.1016/j.ydbio.2010.12.025. Epub 2010 Dec 23. Dev Biol. 2011. PMID: 21185283 Free PMC article.
Rb is critical in a mammalian tissue stem cell population.
Wenzel PL, Wu L, de Bruin A, Chong JL, Chen WY, Dureska G, Sites E, Pan T, Sharma A, Huang K, Ridgway R, Mosaliganti K, Sharp R, Machiraju R, Saltz J, Yamamoto H, Cross JC, Robinson ML, Leone G. Wenzel PL, et al. Genes Dev. 2007 Jan 1;21(1):85-97. doi: 10.1101/gad.1485307. Genes Dev. 2007. PMID: 17210791 Free PMC article.
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G. Chong JL, et al. Nature. 2009 Dec 17;462(7275):930-4. doi: 10.1038/nature08677. Nature. 2009. PMID: 20016602 Free PMC article.
Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis.
Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G. Wu L, et al. Oncogene. 2015 Jan 2;34(1):119-28. doi: 10.1038/onc.2013.511. Epub 2013 Nov 25. Oncogene. 2015. PMID: 24276244 Free PMC article.
12 results