R01 AR063070/AR/NIAMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2013	3
2014	9
2015	15
2016	12
2017	8
2018	7
2019	3
2020	1
2021	5
2022	5
2023	6
2024	2

1

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.

Chen PJ, Hussmann JA, Yan J, Knipping F, Ravisankar P, Chen PF, Chen C, Nelson JW, Newby GA, Sahin M, Osborn MJ, Weissman JS, Adamson B, Liu DR. Chen PJ, et al. Cell. 2021 Oct 28;184(22):5635-5652.e29. doi: 10.1016/j.cell.2021.09.018. Epub 2021 Oct 14. Cell. 2021. PMID: 34653350 Free PMC article.

2

Phage-assisted evolution and protein engineering yield compact, efficient prime editors.

Doman JL, Pandey S, Neugebauer ME, An M, Davis JR, Randolph PB, McElroy A, Gao XD, Raguram A, Richter MF, Everette KA, Banskota S, Tian K, Tao YA, Tolar J, Osborn MJ, Liu DR. Doman JL, et al. Cell. 2023 Aug 31;186(18):3983-4002.e26. doi: 10.1016/j.cell.2023.07.039. Cell. 2023. PMID: 37657419 Free PMC article.

3

Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq.

Malinin NL, Lee G, Lazzarotto CR, Li Y, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Iafrate AJ, Le LP, Aryee MJ, Joung JK, Tsai SQ. Malinin NL, et al. Nat Protoc. 2021 Dec;16(12):5592-5615. doi: 10.1038/s41596-021-00626-x. Epub 2021 Nov 12. Nat Protoc. 2021. PMID: 34773119 Free PMC article. Review.

4

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.

Tsai SQ, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Thapar V, Wyvekens N, Khayter C, Iafrate AJ, Le LP, Aryee MJ, Joung JK. Tsai SQ, et al. Nat Biotechnol. 2015 Feb;33(2):187-197. doi: 10.1038/nbt.3117. Epub 2014 Dec 16. Nat Biotechnol. 2015. PMID: 25513782 Free PMC article.

5

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity.

Neugebauer ME, Hsu A, Arbab M, Krasnow NA, McElroy AN, Pandey S, Doman JL, Huang TP, Raguram A, Banskota S, Newby GA, Tolar J, Osborn MJ, Liu DR. Neugebauer ME, et al. Nat Biotechnol. 2023 May;41(5):673-685. doi: 10.1038/s41587-022-01533-6. Epub 2022 Nov 10. Nat Biotechnol. 2023. PMID: 36357719 Free PMC article.

6

Revertant Mosaicism in Epidermolysis Bullosa.

Meyer-Mueller C, Osborn MJ, Tolar J, Boull C, Ebens CL. Meyer-Mueller C, et al. Biomedicines. 2022 Jan 6;10(1):114. doi: 10.3390/biomedicines10010114. Biomedicines. 2022. PMID: 35052793 Free PMC article. Review.

7

Inside out: regenerative medicine for recessive dystrophic epidermolysis bullosa.

Vanden Oever M, Twaroski K, Osborn MJ, Wagner JE, Tolar J. Vanden Oever M, et al. Pediatr Res. 2018 Jan;83(1-2):318-324. doi: 10.1038/pr.2017.244. Epub 2017 Nov 1. Pediatr Res. 2018. PMID: 29593249 Review.

8

Advances in understanding and treating dystrophic epidermolysis bullosa.

Vanden Oever MJ, Tolar J. Vanden Oever MJ, et al. F1000Prime Rep. 2014 May 6;6:35. doi: 10.12703/P6-35. eCollection 2014. F1000Prime Rep. 2014. PMID: 24860657 Free PMC article. Review.

9

Gene editing and its application for hematological diseases.

Osborn MJ, Belanto JJ, Tolar J, Voytas DF. Osborn MJ, et al. Int J Hematol. 2016 Jul;104(1):18-28. doi: 10.1007/s12185-016-2017-z. Epub 2016 May 27. Int J Hematol. 2016. PMID: 27233509 Free PMC article. Review.

10

A living band-aid for epidermolysis bullosa.

Tolar J, Tolar M. Tolar J, et al. Blood Transfus. 2015 Jan;13(1):1-2. doi: 10.2450/2014.0289-14. Blood Transfus. 2015. PMID: 25636127 Free PMC article. No abstract available.

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