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The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques.
J Virol. 2005 Nov;79(22):14355-70. doi: 10.1128/JVI.79.22.14355-14370.2005.
J Virol. 2005.
PMID: 16254370
Free PMC article.
CD8+ T-lymphocyte response to major immunodominant epitopes after vaginal exposure to simian immunodeficiency virus: too late and too little.
Reynolds MR, Rakasz E, Skinner PJ, White C, Abel K, Ma ZM, Compton L, Napoé G, Wilson N, Miller CJ, Haase A, Watkins DI.
Reynolds MR, et al.
J Virol. 2005 Jul;79(14):9228-35. doi: 10.1128/JVI.79.14.9228-9235.2005.
J Virol. 2005.
PMID: 15994817
Free PMC article.
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Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus.
Miller CJ, Li Q, Abel K, Kim EY, Ma ZM, Wietgrefe S, La Franco-Scheuch L, Compton L, Duan L, Shore MD, Zupancic M, Busch M, Carlis J, Wolinsky S, Haase AT.
Miller CJ, et al.
J Virol. 2005 Jul;79(14):9217-27. doi: 10.1128/JVI.79.14.9217-9227.2005.
J Virol. 2005.
PMID: 15994816
Free PMC article.
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